Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.40 |
| ▸ | ACHE | P22303 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | PIM1 | P11309 | 1/20 | 0.35 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16273134 | 0.86 | MAPT (0.38) | IDO1ACHECYP1A2MAPTALDH1A1 | |
| SCHEMBL15639371 | 0.82 | CYP1A2 (0.46) | IDO1ACHECYP1A2CYP2A6MAPT | |
| SCHEMBL30278835 | 0.82 | CYP1A2 (0.46) | IDO1ACHECYP1A2CYP2A6MAPT | |
| SCHEMBL17899830 | 0.82 | MPI (0.40) | IDO1MAPTALDH1A1POLBKDM4E | |
| SCHEMBL23606174 | 0.79 | CYP1A2 (0.35) | IDO1ACHECYP1A2CYP2A6MAPT | |
| SCHEMBL11710317 | 0.79 | MAPT (0.44) | MAPTALDH1A1KDM4EHPGDEGFR | |
| SCHEMBL23280687 | 0.79 | TDP1 (0.40) | IDO1CYP1A2CYP2A6MAPTPIM1 | |
| SCHEMBL24962714 | 0.79 | ALOX5 (0.42) | ACHECYP1A2CYP2A6MAPTALDH1A1 | |
| SCHEMBL15497381 | 0.79 | PIM1 (0.40) | IDO1CYP1A2CYP2A6MAPTPIM1 | |
| SCHEMBL16273161 | 0.79 | KIF11 (0.37) | IDO1CYP1A2CYP2A6MAPTPIM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140353646-A1 | AROMATIC AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENCE ELEMENT USING SAME | IDEMITSU KOSAN CO., LTD. (JP) | 2014-12-04 | — | — | US | disclosed |
| US-20140353646-A1 | AROMATIC AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENCE ELEMENT USING SAME | IDEMITSU KOSAN CO., LTD. (JP) | 2014-12-04 | — | — | US | disclosed |