Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX4 | Q96LA9 | 6/20 | 0.40 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 3/20 | 0.36 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.34 |
| ▸ | RELA | Q04206 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17616649 | 0.90 | FFAR1 (0.39) | MRGPRX4PTGDR2FFAR1FFAR4MAPT | |
| SCHEMBL16273632 | 0.89 | CYP3A4 (0.37) | MRGPRX4PTGDR2FFAR1FFAR4MAPT | |
| SCHEMBL17677487 | 0.89 | MRGPRX4 (0.45) | MRGPRX4PTGDR2MAPTHDAC8NPC1 | |
| SCHEMBL17616620 | 0.86 | MRGPRX4 (0.40) | MRGPRX4PTGDR2FFAR1FFAR4MAPT | |
| SCHEMBL16273627 | 0.86 | FFAR4 (0.41) | MRGPRX4PTGDR2FFAR1FFAR4MAPT | |
| SCHEMBL17616598 | 0.83 | FFAR4 (0.41) | MRGPRX4PTGDR2FFAR1FFAR4MAPT | |
| SCHEMBL16273633 | 0.83 | MRGPRX4 (0.46) | MRGPRX4FFAR1FFAR4MAPTHDAC8 | |
| SCHEMBL17616618 | 0.82 | CYP3A4 (0.42) | MRGPRX4PTGDR2FFAR1FFAR4MAPT | |
| SCHEMBL17616645 | 0.81 | MRGPRX4 (0.45) | MRGPRX4PTGDR2FFAR1FFAR4MAPT | |
| SCHEMBL16273619 | 0.80 | FFAR4 (0.41) | MRGPRX4FFAR1FFAR4CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9675072-B2 | Tetrazolinone compound and application of same | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2017-06-13 | — | — | US | disclosed |
| EP-3029030-A1 | TETRAZOLINONE COMPOUND, AND USE THEREFOR | Sumitomo Chemical Company, Limited (JP) | 2016-06-08 | — | — | EP | disclosed |
| EP-3006440-A1 | TETRAZOLINONE COMPOUND AND APPLICATION OF SAME | Sumitomo Chemical Company Limited (JP) | 2016-04-13 | — | — | EP | disclosed |
| WO-2015016373-A1 | TETRAZOLINONE COMPOUND, AND USE THEREFOR | 住友化学株式会社 (JP) | 2015-02-05 | — | — | WO | disclosed |
| WO-2014192953-A1 | TETRAZOLINONE COMPOUND AND APPLICATION OF SAME | 住友化学株式会社 (JP) | 2014-12-04 | — | — | WO | disclosed |