SCHEMBL16273619

SCHEMBL16273619

Cc1cc(O)ccc1OCc1ccccc1N=C=O

nearest known ligand 0.41

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
FFAR4 Q5NUL3 6/20 0.41
FFAR1 O14842 3/20 0.41
CD274 Q9NZQ7 6/20 0.38
CYP3A4 P08684 1/20 0.38
MRGPRX4 Q96LA9 3/20 0.38
RECQL P46063 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17616643 0.88 L3MBTL1 (0.43) FFAR4FFAR1CYP3A4MRGPRX4
SCHEMBL16273629 0.87 GABRA1 (0.40) CYP3A4RECQL
SCHEMBL17616618 0.86 CYP3A4 (0.42) FFAR4FFAR1CD274CYP3A4MRGPRX4
SCHEMBL16273632 0.86 CYP3A4 (0.37) FFAR4FFAR1CD274CYP3A4MRGPRX4
SCHEMBL16273633 0.84 MRGPRX4 (0.46) FFAR4FFAR1MRGPRX4
SCHEMBL16273623 0.84 ALDH1A1 (0.38) FFAR4CD274MRGPRX4
SCHEMBL16273615 0.83 MRGPRX4 (0.39) FFAR4FFAR1CYP3A4MRGPRX4
SCHEMBL16273627 0.83 FFAR4 (0.41) FFAR4FFAR1CYP3A4MRGPRX4
SCHEMBL17616598 0.82 FFAR4 (0.41) FFAR4FFAR1CYP3A4MRGPRX4
SCHEMBL17616590 0.82 MRGPRX4 (0.39) FFAR4FFAR1CYP3A4MRGPRX4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9675072-B2 Tetrazolinone compound and application of same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2017-06-13 US disclosed
EP-3029030-A1 TETRAZOLINONE COMPOUND, AND USE THEREFOR Sumitomo Chemical Company, Limited (JP) 2016-06-08 EP disclosed
EP-3006440-A1 TETRAZOLINONE COMPOUND AND APPLICATION OF SAME Sumitomo Chemical Company Limited (JP) 2016-04-13 EP disclosed
WO-2015016373-A1 TETRAZOLINONE COMPOUND, AND USE THEREFOR 住友化学株式会社 (JP) 2015-02-05 WO disclosed
WO-2014192953-A1 TETRAZOLINONE COMPOUND AND APPLICATION OF SAME 住友化学株式会社 (JP) 2014-12-04 WO disclosed