Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 3/20 | 0.37 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | FFAR4 | Q5NUL3 | 5/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.36 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.34 |
| ▸ | CD274 | Q9NZQ7 | 2/20 | 0.33 |
| ▸ | CDK4 | P11802 | 1/20 | 0.33 |
| ▸ | CCND1 | P24385 | 1/20 | 0.33 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.33 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17616618 | 0.91 | CYP3A4 (0.42) | CYP3A4PTGDR2MAPTRAB9ANPSR1 | |
| SCHEMBL16273628 | 0.89 | MRGPRX4 (0.40) | CYP3A4PTGDR2MAPTRAB9AFFAR4 | |
| SCHEMBL16273615 | 0.89 | MRGPRX4 (0.39) | CYP3A4PTGDR2MAPTRAB9ANPSR1 | |
| SCHEMBL16273627 | 0.89 | FFAR4 (0.41) | CYP3A4PTGDR2MAPTRAB9AFFAR4 | |
| SCHEMBL16273619 | 0.86 | FFAR4 (0.41) | CYP3A4FFAR4FFAR1CD274MRGPRX4 | |
| SCHEMBL17616590 | 0.83 | MRGPRX4 (0.39) | CYP3A4PTGDR2MAPTFFAR4FFAR1 | |
| SCHEMBL17616598 | 0.83 | FFAR4 (0.41) | CYP3A4PTGDR2MAPTRAB9ANPSR1 | |
| SCHEMBL17616643 | 0.82 | L3MBTL1 (0.43) | CYP3A4MAPTRAB9AFFAR4FFAR1 | |
| SCHEMBL17616649 | 0.81 | FFAR1 (0.39) | CYP3A4PTGDR2MAPTRAB9AFFAR4 | |
| SCHEMBL17806117 | 0.79 | CYP3A4 (0.40) | CYP3A4PTGDR2MAPTFFAR4FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9675072-B2 | Tetrazolinone compound and application of same | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2017-06-13 | — | — | US | disclosed |
| EP-3029030-A1 | TETRAZOLINONE COMPOUND, AND USE THEREFOR | Sumitomo Chemical Company, Limited (JP) | 2016-06-08 | — | — | EP | disclosed |
| EP-3006440-A1 | TETRAZOLINONE COMPOUND AND APPLICATION OF SAME | Sumitomo Chemical Company Limited (JP) | 2016-04-13 | — | — | EP | disclosed |
| WO-2015016373-A1 | TETRAZOLINONE COMPOUND, AND USE THEREFOR | 住友化学株式会社 (JP) | 2015-02-05 | — | — | WO | disclosed |
| WO-2014192953-A1 | TETRAZOLINONE COMPOUND AND APPLICATION OF SAME | 住友化学株式会社 (JP) | 2014-12-04 | — | — | WO | disclosed |