Known targets — ChEMBL curated mechanism
S1PR1S1PR2S1PR3S1PR4S1PR5rplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 2/20 | 0.91 |
| ▸ | TSHR | P16473 | 2/20 | 0.91 |
| ▸ | GLA | P06280 | 1/20 | 0.91 |
| ▸ | HPGD | P15428 | 1/20 | 0.91 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.91 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.91 |
| ▸ | BLM | P54132 | 1/20 | 0.91 |
| ▸ | CA1 | P00915 | 15/20 | 0.59 |
| ▸ | CA2 | P00918 | 15/20 | 0.59 |
| ▸ | CA9 | Q16790 | 13/20 | 0.59 |
| ▸ | CA12 | O43570 | 4/20 | 0.59 |
| ▸ | CA7 | P43166 | 4/20 | 0.59 |
| ▸ | CA14 | Q9ULX7 | 4/20 | 0.59 |
| ▸ | CA3 | P07451 | 3/20 | 0.59 |
| ▸ | CA4 | P22748 | 3/20 | 0.59 |
| ▸ | CA6 | P23280 | 3/20 | 0.59 |
| ▸ | CA5A | P35218 | 3/20 | 0.59 |
| ▸ | CA5B | Q9Y2D0 | 3/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21550444 | 0.95 | RECQL (0.91) | RECQLTSHRGLAHPGDMAPK1 | |
| SCHEMBL22283884 | 0.95 | RECQL (0.91) | RECQLTSHRGLAHPGDMAPK1 | |
| SCHEMBL22390647 | 0.95 | RECQL (1.00) | RECQLTSHRGLAHPGDMAPK1 | |
| SCHEMBL25262176 | 0.95 | RECQL (1.00) | RECQLTSHRGLAHPGDMAPK1 | |
| SCHEMBL22390687 | 0.95 | RECQL (1.00) | RECQLTSHRGLAHPGDMAPK1 | |
| Lithium Ion SCHEMBL25256858 | 0.95 | RECQL (0.91) | RECQLTSHRGLAHPGDMAPK1 | |
| SCHEMBL22390764 | 0.95 | RECQL (1.00) | RECQLTSHRGLAHPGDMAPK1 | |
| SCHEMBL23387500 | 0.95 | RECQL (1.00) | RECQLTSHRGLAHPGDMAPK1 | |
| SCHEMBL22283886 | 0.95 | RECQL (0.91) | RECQLTSHRGLAHPGDMAPK1 | |
| SCHEMBL22283888 | 0.95 | RECQL (0.91) | RECQLTSHRGLAHPGDMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7927516-B2 | Method for synthesis of colloidal nanoparticles | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2011-04-19 | — | — | US | disclosed |
| US-7615169-B2 | Method for synthesis of colloidal nanoparticles | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2009-11-10 | — | — | US | disclosed |
| US-7575699-B2 | Method for synthesis of colloidal nanoparticles | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2009-08-18 | — | — | US | disclosed |
| US-20070264834-A1 | Method for Synthesis of Colloidal Nanoparticles | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2007-11-15 | — | — | US | disclosed |
| WO-2006034280-A2 | METHOD FOR SYNTHESIS OF COLLOIDAL NANOPARTICLES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2006-03-30 | — | — | WO | disclosed |
| US-20060060998-A1 | Method for synthesis of colloidal nanoparticles | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2006-03-23 | — | — | US | disclosed |
| US-20060061017-A1 | Method for synthesis of colloidal nanoparticles | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2006-03-23 | — | — | US | disclosed |
| EP-0746755-A4 | A SOLID STATE SENSOR FOR CARBON MONOXIDE | FIBERCHEM INC (US) | 1997-11-12 | — | — | EP | disclosed |
| EP-0746755-A1 | A SOLID STATE SENSOR FOR CARBON MONOXIDE | FCI-FIBERCHEM, INC. (US) | 1996-12-11 | — | — | EP | disclosed |
| US-5405583-A | Solid state sensor for carbon monoxide | FCI - FIBERCHEM, INC. (US) | 1995-04-11 | — | — | US | disclosed |
| WO-1994017390-A1 | A SOLID STATE SENSOR FOR CARBON MONOXIDE | FCI-FIBERCHEM, INC. (US) | 1994-08-04 | — | — | WO | disclosed |