SCHEMBL1627397

SCHEMBL1627397

Cc1cc(CO)ccc1C(=O)O

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NR1H4 Q96RI1 1/20 0.51
RARB P10826 1/20 0.50
HMGB1 P09429 1/20 0.47
CXCL12 P48061 1/20 0.47
RXRA P19793 2/20 0.47
CA12 O43570 1/20 0.46
CA1 P00915 1/20 0.46
CA2 P00918 1/20 0.46
CA3 P07451 1/20 0.46
CA4 P22748 1/20 0.46
CA6 P23280 1/20 0.46
CA7 P43166 1/20 0.46
CA9 Q16790 1/20 0.46
CA14 Q9ULX7 1/20 0.46
CA5B Q9Y2D0 1/20 0.46
RXRB P28702 2/20 0.45
PTGER4 P35408 3/20 0.44
ACMSD Q8TDX5 1/20 0.44
SMN1; SMN2 Q16637 2/20 0.41
TSHR P16473 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL107902 0.86 HMGB1 (0.58) NR1H4RARBHMGB1CXCL12RXRA
SCHEMBL23927631 0.85 RARB (0.51) NR1H4RARBHMGB1CXCL12RXRA
SCHEMBL15238379 0.84 CYP4F2 (0.46) NR1H4RARBCA12CA2CA3
SCHEMBL5225010 0.84 HMGB1 (0.47) HMGB1CXCL12CA12CA1CA2
SCHEMBL2343149 0.84 ALDH1A1 (0.55) NR1H4RARBHMGB1CXCL12RXRA
SCHEMBL1712181 0.82 NR1H4 (0.50) NR1H4RARBHMGB1CXCL12RXRA
SCHEMBL10083231 0.82 NR1H4 (0.50) NR1H4RARBHMGB1CXCL12RXRA
SCHEMBL1146167 0.82 NR1H4 (0.50) NR1H4RARBHMGB1CXCL12RXRA
SCHEMBL33493 0.82 NR1H4 (0.50) NR1H4RARBHMGB1CXCL12RXRA
SCHEMBL7025446 0.82 NR1H4 (0.50) NR1H4RARBHMGB1CXCL12RXRA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 98 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114113390-B Florarana intermediate and detection method of impurities thereof 丽珠集团新北江制药股份有限公司 2023-05-23 CN claimed
CN-114113390-A Method for detecting flurarana intermediate and impurities thereof 丽珠集团新北江制药股份有限公司 2022-03-01 CN claimed
EP-1349878-B1 METHOD FOR PRODUCING A CATALYST FOR HOMO- OR CO-POLYMERIZATION OF ETHYLENE SAMSUNG GENERAL CHEMICALS CO (KR) 2009-04-22 EP claimed
EP-1339761-B1 METHOD FOR PRODUCING HOMO- AND CO-POLYMERS OF ETHYLENE SAMSUNG GENERAL CHEMICALS CO (KR) 2007-03-14 EP claimed
EP-1307492-B1 A CATALYST FOR ETHYLENE HOMO- AND COPOLYMERIZATION SAMSUNG GENERAL CHEMICALS CO (KR) 2006-11-02 EP claimed
EP-1276776-B1 CATALYST FOR PRODUCING AN ULTRA HIGH MOLECULAR WEIGHT POLYETHYLENE AND METHOD FOR PRODUCING AN ULTRA HIGH MOLECULAR WEIGHT POLYETHYLENE USING THE SAME SAMSUNG GENERAL CHEMICALS CO (KR) 2006-11-02 EP claimed
US-7129303-B2 Method for producing homo- and co-polymers of ethylene SAMSUNG ATOFINA CO., LTD. (KR) 2006-10-31 US claimed
EP-1355952-B1 METHOD FOR PRODUCING A CATALYST FOR HOMO- OR CO- POLYMERIZATION OF ETHYLENE SAMSUNG GENERAL CHEMICALS CO (KR) 2006-08-23 EP claimed
EP-1339760-B1 METHOD FOR PRODUCING HOMO- AND CO-POLYMERS OF ETHYLENE SAMSUNG GENERAL CHEMICALS CO (KR) 2006-08-16 EP claimed
EP-1287043-B1 A METHOD FOR PRODUCING ETHYLENE HOMO- AND CO-POLYMER SAMSUNG GENERAL CHEMICALS CO (KR) 2005-11-23 EP claimed
US-6914028-B2 Method for producing a catalyst for homo-or co-polymerization of ethylene SAMSUNG ATOFINA CO., LTD. (KR) 2005-07-05 US claimed
EP-1075833-B1 Barrier cream SECR DEFENCE (GB) 2005-04-13 EP claimed
EP-1203034-B1 A CATALYST FOR ETHYLENE HOMO- AND CO-POLYMERIZATION SAMSUNG GENERAL CHEMICALS CO (KR) 2004-08-25 EP claimed
EP-1194455-B1 A CATALYST FOR ETHYLENE HOMO- AND CO-POLYMERIZATION SAMSUNG GENERAL CHEMICALS CO (KR) 2004-08-25 EP claimed
EP-0813516-B1 PROCESS FOR THE PREPARATION OF STILBENEDICARBOXYLATE ESTERS EASTMAN CHEM CO (US) 1999-12-01 EP claimed
US-20240245673-A1 Papain-like protease (PLpro) inhibitors PFIZER INC. (US) 2024-07-25 US disclosed
WO-2024121779-A1 PAPAIN-LIKE PROTEASE (PLPRO) INHIBITORS PFIZER INC. (US) 2024-06-13 WO disclosed
EP-0204571-A2 Selected difluoro derivatives ICI AMERICAS INC. (US) 1986-12-10 EP disclosed
EP-0189305-A2 Peptide derivatives ICI AMERICAS INC. (US) 1986-07-30 EP disclosed
US-4528361-A Copolymers of hydroxymethylbenzoic acid and lactam STANDARD OIL COMPANY (INDIANA) (US) 1985-07-09 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240245673-A1 Papain-like protease (PLpro) inhibitors PREP, PEPD, ACE NR1H4 3222/4885RARB 3523/4885HMGB1 3687/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.