Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.50 |
| ▸ | RARB | P10826 | 1/20 | 0.49 |
| ▸ | RXRA | P19793 | 2/20 | 0.46 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.46 |
| ▸ | CXCL12 | P48061 | 1/20 | 0.46 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.45 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.45 |
| ▸ | CES2 | O00748 | 1/20 | 0.44 |
| ▸ | CES1 | P23141 | 1/20 | 0.44 |
| ▸ | RXRB | P28702 | 2/20 | 0.44 |
| ▸ | CFD | P00746 | 1/20 | 0.41 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.40 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.40 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.40 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.40 |
| ▸ | CTSB | P07858 | 1/20 | 0.40 |
| ▸ | MMP9 | P14780 | 1/20 | 0.40 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.40 |
| ▸ | DNMT3B | Q9UBC3 | 1/20 | 0.40 |
| ▸ | DNMT3L | Q9UJW3 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31568856 | 0.85 | RARB (0.50) | NR1H4RARBRXRAHMGB1CXCL12 | |
| SCHEMBL1020426 | 0.85 | RARB (0.50) | NR1H4RARBRXRAHMGB1CXCL12 | |
| SCHEMBL1179532 | 0.85 | CYP4F2 (0.49) | NR1H4RARBHMGB1CXCL12CYP4F2 | |
| SCHEMBL9403206 | 0.84 | ALDH1A1 (0.47) | NR1H4RARBCES2CES1CFD | |
| SCHEMBL107902 | 0.84 | HMGB1 (0.58) | NR1H4RARBRXRAHMGB1CXCL12 | |
| SCHEMBL31635558 | 0.83 | CYP4F2 (0.47) | NR1H4RARBRXRAHMGB1CXCL12 | |
| SCHEMBL6223649 | 0.83 | CYP4F2 (0.44) | NR1H4CYP4F2CYP4A11CES2CES1 | |
| SCHEMBL1627397 | 0.82 | NR1H4 (0.51) | NR1H4RARBRXRAHMGB1CXCL12 | |
| SCHEMBL2343149 | 0.82 | ALDH1A1 (0.55) | NR1H4RARBRXRAHMGB1CXCL12 | |
| SCHEMBL2857663 | 0.82 | KLKB1 (0.48) | CYP4F2CYP4A11CES2CES1CFD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 363 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114414684-B | Florarana intermediate and detection method of isomer thereof | 丽珠集团新北江制药股份有限公司 | 2023-05-23 | — | — | CN | claimed |
| US-20250170266-A1 | IMMUNOMODULATOR PURINE-DERIVED COMPOUNDS, CONJUGATES THEREOF, AND METHODS OF USE THEREOF | ZYMEWORKS BC INC. (CA) | 2025-05-29 | — | — | US | disclosed |
| US-20250109095-A1 | METHOD FOR PREPARING OXIME DERIVATIVE | SEOUL NATIONAL UNIVERSITY R&DB FOUNDATION (KR) | 2025-04-03 | — | — | US | disclosed |
| US-12054471-B2 | Thiocycloheptyne derivatives and their use | CRISTAL DELIVERY B.V. (NL) | 2024-08-06 | — | — | US | disclosed |
| WO-2024105159-A1 | LIGANDS OF THE M6A-RNA READERS | UNIVERSITY OF ZURICH (CH) | 2024-05-23 | — | — | WO | disclosed |
| WO-2024020684-A1 | IMMUNOMODULATOR PURINE-DERIVED COMPOUNDS, CONJUGATES THEREOF, AND METHODS OF USE THEREOF | ZYMEWORKS BC INC. (CA) | 2024-02-01 | — | — | WO | disclosed |
| CN-112707809-B | Method for preparing oxazoline insecticide fluorine Lei Lana intermediate | 丽珠集团新北江制药股份有限公司 | 2023-08-29 | — | — | CN | disclosed |
| CN-114763356-B | Pyrrolo-benzodiazepine compound, and preparation method and application thereof | 沈阳药科大学 | 2023-06-20 | — | — | CN | disclosed |
| WO-2023104165-A1 | PYRIDINE[4,3-D]PYRIMIDINE COMPOUND AS TLR7/8 AGONIST | 上海维申医药有限公司 | 2023-06-15 | — | — | WO | disclosed |
| WO-2023101319-A1 | METHOD FOR PREPARING OXIME DERIVATIVE | 서울대학교산학협력단 | 2023-06-08 | — | — | WO | disclosed |
| US-5171748-A | For hypertension, cardiovascular disorders | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1992-12-15 | — | — | US | disclosed |
| US-5053164-A | For high speed switching | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1991-10-01 | — | — | US | disclosed |
| EP-0110405-B1 | ANTIINFLAMMATORY/ANTIALLERGIC COMPOUNDS | RORER INTERNATIONAL (OVERSEAS) INC. (a Delaware corporation) (US) | 1990-12-27 | — | — | EP | disclosed |
| EP-0399732-A1 | Benzimidazole derivatives | ZENECA LIMITED (GB) | 1990-11-28 | — | — | EP | disclosed |
| US-4943651-A | Novel substitued naphthalene compounds and liquid crystal compositions containing same | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1990-07-24 | — | — | US | disclosed |
| EP-0332409-A2 | Novel substituted naphthalene compounds and liquid crystal compositions containing same | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1989-09-13 | — | — | EP | disclosed |
| US-4866076-A | THROMBOXANE ANTAGONISTS | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1989-09-12 | — | — | US | disclosed |
| US-4778931-A | ENZYME INHIBITORS | USV PHARMACEUTICAL CORPORATION (US) | 1988-10-18 | — | — | US | disclosed |
| US-4567184-A | Certain aryl or hetero-aryl derivatives of 1-hydroxy-pentane or 1-hydroxy-hexane which are useful for treating inflammation and allergies | USV PHARMACEUTICAL CORPORATION (US) | 1986-01-28 | — | — | US | disclosed |
| EP-0110405-A2 | Antiinflammatory/antiallergic compounds | RORER INTERNATIONAL (OVERSEAS) INC. (a Delaware corporation) (US) | 1984-06-13 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250109095-A1 | METHOD FOR PREPARING OXIME DERIVATIVE | NOS2, NOS1, NOS3 | NR1H4 4836/4885RARB 2660/4885RXRA 3623/4885 |
| US-12054471-B2 | Thiocycloheptyne derivatives and their use | CYP7A1, CYP3A5, ABCB1 | NR1H4 86/4885RARB 3563/4885RXRA 4104/4885 |
| US-20250170266-A1 | IMMUNOMODULATOR PURINE-DERIVED COMPOUNDS, CONJUGATES THEREOF, AND METHODS OF USE THEREOF | PAICS, ENTPD5, PNP | NR1H4 686/4885RARB 842/4885RXRA 843/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.