Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.46 |
| ▸ | TSHR | P16473 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 4/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.42 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.42 |
| ▸ | PPIA | P62937 | 2/20 | 0.42 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16274655 | 0.88 | POLB (0.47) | POLBSMN1; SMN2ALDH1A1KDM4ELMNA | |
| SCHEMBL16274872 | 0.87 | POLB (0.46) | POLBSMN1; SMN2ALDH1A1KDM4ELMNA | |
| SCHEMBL16274596 | 0.87 | JAK2 (0.49) | POLBSMN1; SMN2ALDH1A1KDM4ELMNA | |
| SCHEMBL3515532 | 0.82 | PPIA (0.51) | POLBSMN1; SMN2TSHRRAB9ANPC1 | |
| SCHEMBL16274738 | 0.80 | AGTR1 (0.48) | POLBSMN1; SMN2TSHRALDH1A1KDM4E | |
| SCHEMBL25541334 | 0.79 | TDP1 (0.54) | POLBSMN1; SMN2TSHRALDH1A1LMNA | |
| SCHEMBL1522564 | 0.77 | HTT (0.62) | POLBSMN1; SMN2TSHRALDH1A1RAB9A | |
| SCHEMBL15166669 | 0.75 | POLB (0.44) | POLBSMN1; SMN2TSHRALDH1A1LMNA | |
| SCHEMBL16274827 | 0.75 | POLB (0.46) | POLBSMN1; SMN2ALDH1A1KDM4ELMNA | |
| SCHEMBL16274916 | 0.75 | RAB9A (0.53) | POLBSMN1; SMN2TSHRALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2810944-A1 | HETEROCYCLIC COMPOUND HAVING ANTI-HIV ACTIVITY | Toyama Chemical Co., Ltd. (JP) | 2014-12-10 | — | — | EP | disclosed |