SCHEMBL1627490

SCHEMBL1627490

CC(C)(C)[Si](C)(C)OCCCCc1ccc(CBr)cc1

nearest known ligand 0.40

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
DUT P33316 2/20 0.40
KCNH2 Q12809 1/20 0.33
TDP1 Q9NUW8 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31
IDO1 P14902 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9701756 0.88 DUT (0.36) DUT
SCHEMBL12284225 0.87 DUT (0.40) DUTL3MBTL1IDO1
SCHEMBL11897958 0.86 DUT (0.39) DUTTDP1L3MBTL1IDO1
SCHEMBL1171890 0.86 PREP (0.40) DUTTDP1L3MBTL1
SCHEMBL1629726 0.85 IGF1R (0.41) DUTKCNH2
SCHEMBL9321623 0.84 DUT (0.34) DUT
SCHEMBL1627173 0.84 DUT (0.40) DUTKCNH2
SCHEMBL1627500 0.84 DUT (0.40) DUTTDP1
SCHEMBL27834052 0.84 DUT (0.40) DUTKCNH2TDP1L3MBTL1IDO1
SCHEMBL17398452 0.83 IDO1 (0.47) DUTTDP1L3MBTL1IDO1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 48 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210300878-A1 CONTRAST AGENTS FOR MYOCARDIAL PERFUSION IMAGING LANTHEUS MEDICAL IMAGING, INC. (US) 2021-09-30 US disclosed
EP-3385253-B1 CONTRAST AGENTS FOR MYOCARDIAL PERFUSION IMAGING LANTHEUS MEDICAL IMAGING INC (US) 2021-04-07 EP disclosed
EP-3385253-B1 CONTRAST AGENTS FOR MYOCARDIAL PERFUSION IMAGING LANTHEUS MEDICAL IMAGING INC (US) 2021-04-07 EP disclosed
US-10889550-B2 Contrast agents for myocardial perfusion imaging LANTHEUS MEDICAL IMAGING, INC. (US) 2021-01-12 US disclosed
EP-2257315-B1 CONTRAST AGENTS FOR APPLICATIONS INCLUDING PERFUSION IMAGING LANTHEUS MEDICAL IMAGING INC (US) 2019-10-23 EP disclosed
EP-2257315-B1 CONTRAST AGENTS FOR APPLICATIONS INCLUDING PERFUSION IMAGING LANTHEUS MEDICAL IMAGING INC (US) 2019-10-23 EP disclosed
US-20190127333-A1 CONTRAST AGENTS FOR MYOCARDIAL PERFUSION IMAGING LANTHEUS MEDICAL IMAGING, INC. (US) 2019-05-02 US disclosed
US-10245332-B2 Contrast agents for applications including perfusion imaging LANTHEUS MEDICAL IMAGING, INC. (US) 2019-04-02 US disclosed
US-10125106-B2 Contrast agents for myocardial perfusion imaging LANTHEUS MEDICAL IMAGING, INC. (US) 2018-11-13 US disclosed
EP-3385253-A1 CONTRAST AGENTS FOR MYOCARDIAL PERFUSION IMAGING Lantheus Medical Imaging, Inc. (US) 2018-10-10 EP disclosed
EP-2257315-A2 CONTRAST AGENTS FOR APPLICATIONS INCLUDING PERFUSION IMAGING Lantheus Medical Imaging, Inc. (US) 2010-12-08 EP disclosed
WO-2009110984-A2 CONTRAST AGENTS FOR APPLICATIONS INCLUDING PERFUSION IMAGING LANTHEUS MEDICAL IMAGING, INC. (US) 2009-09-11 WO disclosed
EP-1713512-A4 CONTRAST AGENTS FOR MYOCARDIAL PERFUSION IMAGING BRISTOL MYERS SQUIBB PHARMA CO (US) 2009-01-07 EP disclosed
US-20080112884-A1 CONTRAST AGENTS FOR MYOCARDIAL PERFUSION IMAGING BRISTOL-MYERS SQUIBB PHARMA COMPANY 2008-05-15 US disclosed
US-20080112884-A1 CONTRAST AGENTS FOR MYOCARDIAL PERFUSION IMAGING BRISTOL-MYERS SQUIBB PHARMA COMPANY 2008-05-15 US disclosed
US-7344702-B2 Contrast agents for myocardial perfusion imaging BRISTOL-MYERS SQUIBB PHARMA COMPANY (US) 2008-03-18 US disclosed
US-7344702-B2 Contrast agents for myocardial perfusion imaging BRISTOL-MYERS SQUIBB PHARMA COMPANY (US) 2008-03-18 US disclosed
EP-1713512-A2 CONTRAST AGENTS FOR MYOCARDIAL PERFUSION IMAGING Bristol-Myers Squibb Pharma Company (US) 2006-10-25 EP disclosed
WO-2005079391-A2 CONTRAST AGENTS FOR MYOCARDIAL PERFUSION IMAGING BRISTOL-MYERS SQUIBB PHARMA COMPANY (US) 2005-09-01 WO disclosed
US-20050191238-A1 Contrast agents for myocardial perfusion imaging LANTHEUS MEDICAL IMAGING, INC. 2005-09-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080112884-A1 CONTRAST AGENTS FOR MYOCARDIAL PERFUSION IMAGING TNNI3, TNNT2, FABP3 DUT 572/4885KCNH2 1415/4885TDP1 2236/4885
US-20050191238-A1 Contrast agents for myocardial perfusion imaging TNNI3, TNNT2, FABP3 DUT 572/4885KCNH2 1415/4885TDP1 2236/4885
US-10245332-B2 Contrast agents for applications including perfusion imaging MCOLN1, CNR1, SLC5A7 DUT 1518/4885KCNH2 1995/4885TDP1 1843/4885
US-20190127333-A1 CONTRAST AGENTS FOR MYOCARDIAL PERFUSION IMAGING TNNI3, TNNT2, FABP3 DUT 572/4885KCNH2 1415/4885TDP1 2236/4885
US-10125106-B2 Contrast agents for myocardial perfusion imaging TNNI3, TNNT2, FABP3 DUT 572/4885KCNH2 1415/4885TDP1 2236/4885
US-20210300878-A1 CONTRAST AGENTS FOR MYOCARDIAL PERFUSION IMAGING TNNI3, TNNT2, FABP3 DUT 572/4885KCNH2 1415/4885TDP1 2236/4885
US-10889550-B2 Contrast agents for myocardial perfusion imaging TNNI3, TNNT2, FABP3 DUT 572/4885KCNH2 1415/4885TDP1 2236/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.