Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | MRGPRX1 | Q96LB2 | 1/20 | 0.47 |
| ▸ | CASP1 | P29466 | 1/20 | 0.47 |
| ▸ | ACHE | P22303 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7330805 | 0.86 | TP53 (0.54) | TP53POLBALDH1A1HPGDLMNA | |
| SCHEMBL31570128 | 0.84 | TP53 (0.53) | TP53POLBALDH1A1HPGDLMNA | |
| SCHEMBL31146391 | 0.82 | ALDH1A1 (0.65) | POLBALDH1A1LMNAHTTNPSR1 | |
| SCHEMBL9191016 | 0.82 | ALDH1A1 (0.65) | POLBALDH1A1LMNAHTTNPSR1 | |
| SCHEMBL2088830 | 0.80 | ALDH1A1 (0.51) | TP53POLBALDH1A1HPGDLMNA | |
| SCHEMBL105237 | 0.80 | BRD4 (0.55) | TP53POLBALDH1A1HPGDLMNA | |
| SCHEMBL2088832 | 0.80 | ALDH1A1 (0.51) | TP53POLBALDH1A1HPGDLMNA | |
| SCHEMBL5203410 | 0.80 | IRAK4 (0.59) | TP53POLBALDH1A1GAAMRGPRX1 | |
| SCHEMBL29832117 | 0.79 | GAA (0.77) | POLBALDH1A1LMNAGAAKMT2A | |
| SCHEMBL11396133 | 0.79 | HSD17B10 (0.50) | POLBALDH1A1HPGDLMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014192865-A1 | PHENYLPIPERAZINE DERIVATIVE | 大日本住友製薬株式会社 (JP) | 2014-12-04 | — | — | WO | disclosed |