SCHEMBL11396133

SCHEMBL11396133

CC(=O)Oc1ccccc1NC(=O)CBr

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 3/20 0.50
GAA P10253 1/20 0.50
ALDH1A1 P00352 3/20 0.47
TOP1 P11387 2/20 0.47
POLB P06746 2/20 0.47
MEN1 O00255 1/20 0.47
KMT2A Q03164 1/20 0.47
CYP2C19 P33261 1/20 0.46
SMN1; SMN2 Q16637 1/20 0.45
TSHR P16473 3/20 0.45
KDM4E B2RXH2 1/20 0.45
ESR1 P03372 1/20 0.45
ITGB3 P05106 1/20 0.45
ITGA2B P08514 1/20 0.45
HMGB1 P09429 1/20 0.45
HPGD P15428 1/20 0.45
GGT1 P19440 1/20 0.45
PTGS1 P23219 1/20 0.45
PTGS2 P35354 1/20 0.45
BLM P54132 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31146391 0.83 ALDH1A1 (0.65) HSD17B10ALDH1A1POLBMEN1KMT2A
SCHEMBL9191016 0.83 ALDH1A1 (0.65) HSD17B10ALDH1A1POLBMEN1KMT2A
SCHEMBL6905859 0.81 HSD17B10 (0.51) HSD17B10GAAALDH1A1TOP1POLB
SCHEMBL8886874 0.81 HSD17B10 (0.66) HSD17B10ALDH1A1TOP1POLBMEN1
SCHEMBL8478426 0.81 HSD17B10 (0.45) HSD17B10GAAALDH1A1POLBMEN1
SCHEMBL6424910 0.81 GAA (0.77) GAAALDH1A1POLBMEN1KMT2A
SCHEMBL29832117 0.81 GAA (0.77) GAAALDH1A1POLBMEN1KMT2A
SCHEMBL16276256 0.79 TP53 (0.53) GAAALDH1A1POLBMEN1KMT2A
SCHEMBL6907717 0.79 HSD17B10 (0.46) HSD17B10GAAALDH1A1TOP1POLB
SCHEMBL6904191 0.79 KMT2A (0.55) HSD17B10GAAALDH1A1TOP1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4288605-A BACTERIOSTAT, FUNGISTAT STAUFFER CHEMICAL COMPANY (US) 1981-09-08 US disclosed