SCHEMBL16277258

SCHEMBL16277258

C[Si](C)(C)OC1(C(F)(F)F)c2ccccc2C(O[Si](C)(C)C)(C(F)(F)F)c2cc3c(cc21)C(O[Si](C)(C)C)(C(F)(F)F)c1ccccc1C3(O[Si](C)(C)C)C(F)(F)F

nearest known ligand 0.35

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
PDK2 Q15119 20/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15203038 0.94 PDK2 (0.38) PDK2
SCHEMBL15203217 0.89 PDK2 (0.35) PDK2
SCHEMBL30537696 0.81
SCHEMBL30537676 0.68
SCHEMBL28724216 0.68
SCHEMBL16276535 0.65 HTR5A (0.32) PDK2
SCHEMBL16276541 0.63 CYP1A2 (0.34)
SCHEMBL9861333 0.63 KCNQ2 (0.42) PDK2
SCHEMBL15203040 0.60 PDK2 (0.67) PDK2
SCHEMBL9455472 0.59 PDK2 (0.34) PDK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9087996-B2 Fluorine-containing aromatic compound and production method thereof ASAHI GLASS COMPANY, LIMITED (JP) 2015-07-21 US disclosed
US-20140357873-A1 FLUORINE-CONTAINING AROMATIC COMPOUND AND PRODUCTION METHOD THEREOF AGC Inc. (JP) 2014-12-04 US disclosed