Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 15/20 | 0.34 |
| ▸ | MAOA | P21397 | 2/20 | 0.33 |
| ▸ | MAOB | P27338 | 2/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
| ▸ | AHR | P35869 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | RECQL | P46063 | 1/20 | 0.30 |
| ▸ | BLM | P54132 | 1/20 | 0.30 |
| ▸ | SMAD3 | P84022 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.30 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.30 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9732686 | 0.90 | PDK2 (0.40) | PDK2MAOAMAOBALOX5AHR | |
| SCHEMBL29617163 | 0.90 | PDK2 (0.40) | PDK2MAOAMAOBALOX5AHR | |
| SCHEMBL9455519 | 0.76 | PDK2 (0.31) | PDK2 | |
| SCHEMBL9455536 | 0.76 | — | — | |
| SCHEMBL21104345 | 0.75 | TDP2 (0.32) | TDP1 | |
| SCHEMBL9616256 | 0.72 | PDK2 (0.50) | PDK2 | |
| SCHEMBL3473632 | 0.72 | PDK2 (0.42) | PDK2MEN1MAPTHPGDKMT2A | |
| SCHEMBL30884612 | 0.72 | PDK2 (0.41) | PDK2MEN1MAPTHPGDKMT2A | |
| SCHEMBL30397838 | 0.72 | PDK2 (0.42) | PDK2MEN1MAPTHPGDKMT2A | |
| SCHEMBL8644400 | 0.72 | FTO (0.44) | PDK2MEN1MAPTHPGDCYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5189138-A | COMPOUNDS, MONOMERS, AND POLYMERS BASED ON PERFLUOROALKYL AND PERFLUOROALKYL-ARYL DIOXAPENTACENE | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1993-02-23 | — | — | US | disclosed |
| EP-0500026-A1 | Compounds, monomers, and polymers based on perfluoroalkyl and perfluoroalkyl-aryl dioxapentacene | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1992-08-26 | — | — | EP | disclosed |