SCHEMBL1628028

SCHEMBL1628028

CCOP(C)(=O)Cc1cc2c(cc1CP(C)(=O)OCC)-c1cccc3cccc-2c13

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.41
HPGD P15428 3/20 0.41
CASP1 P29466 3/20 0.41
TSHR P16473 2/20 0.41
MAPK1 P28482 2/20 0.41
HSD17B10 Q99714 2/20 0.41
CASP7 P55210 2/20 0.41
TP53 P04637 1/20 0.41
HIF1A Q16665 1/20 0.41
CYP1B1 Q16678 1/20 0.37
KDM4E B2RXH2 3/20 0.36
LMNA P02545 1/20 0.36
ATM Q13315 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
TDP1 Q9NUW8 1/20 0.35
FGFR1 P11362 1/20 0.35
FLT1 P17948 1/20 0.35
FGFR3 P22607 1/20 0.35
CES2 O00748 1/20 0.34
BCHE P06276 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1687837 0.87 ALDH1A1 (0.42) ALDH1A1HPGDCASP1TSHRMAPK1
SCHEMBL10146809 0.74 ACP3 (0.56) ALDH1A1HPGDKDM4ELMNAATM
SCHEMBL1628637 0.71 TSHR (0.34) TSHRTP53LMNATDP1GAA
SCHEMBL21323909 0.68 ALDH1A1 (0.48) ALDH1A1HPGDCASP1TSHRMAPK1
SCHEMBL9170876 0.68 KDM4E (0.41) HPGDTSHRKDM4ELMNANR1I2
SCHEMBL11957240 0.67 KDM4E (0.48) ALDH1A1HPGDKDM4ELMNAL3MBTL1
SCHEMBL15396608 0.65 NPSR1 (0.48) HPGDTSHRTP53NR1I2NPSR1
Naftalofos SCHEMBL117809 0.65 TDP1 (0.58) ALDH1A1HPGDCASP1HSD17B10CYP1B1
Naftalofos SCHEMBL30183163 0.65 TDP1 (0.58) ALDH1A1HPGDCASP1HSD17B10CYP1B1
SCHEMBL3923029 0.65 HDAC1 (0.35) HPGDKDM4ELMNANPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8519613-B2 Organic light-emitting device CANON KABUSHIKI KAISHA (JP) 2013-08-27 US disclosed
US-20120085996-A1 ORGANIC LIGHT-EMITTING DEVICE CANON KABUSHIKI KAISHA (JP) 2012-04-12 US disclosed