SCHEMBL1628637

SCHEMBL1628637

CCOP(C)(=O)Cc1cc(Br)c(Br)cc1CP(C)(=O)OCC

nearest known ligand 0.36

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.34
MAPT P10636 1/20 0.33
HTT P42858 1/20 0.33
TP53 P04637 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
NPSR1 Q6W5P4 1/20 0.32
POLB P06746 2/20 0.31
MEN1 O00255 1/20 0.31
GAA P10253 1/20 0.31
KMT2A Q03164 1/20 0.31
KCNH2 Q12809 1/20 0.31
LMNA P02545 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10022793 0.82 MAPT (0.44) TSHRMAPTHTTTP53TDP1
SCHEMBL31252630 0.76 POLB (0.35) MAPTHTTPOLBGAAKMT2A
SCHEMBL1459085 0.75 POLB (0.36) TSHRMAPTTDP1POLBMEN1
SCHEMBL18157316 0.75 LMNA (0.38) MAPTNPSR1POLBMEN1GAA
SCHEMBL3373620 0.74 MAPT (0.44) TSHRMAPTHTTTP53TDP1
SCHEMBL31252590 0.73 NOTUM (0.42) TSHRMAPTHTTTP53NPSR1
SCHEMBL17263482 0.73 CYP1A2 (0.35) POLBMEN1GAAKMT2ALMNA
SCHEMBL12709305 0.72 KMT2A (0.41) NPSR1POLBMEN1GAAKMT2A
SCHEMBL1628028 0.71 ALDH1A1 (0.41) TSHRTP53TDP1NPSR1GAA
SCHEMBL31252585 0.70 CYP4F2 (0.34) NPSR1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8519613-B2 Organic light-emitting device CANON KABUSHIKI KAISHA (JP) 2013-08-27 US disclosed
US-20120085996-A1 ORGANIC LIGHT-EMITTING DEVICE CANON KABUSHIKI KAISHA (JP) 2012-04-12 US disclosed