Zinc Ion

Zinc Ion

SCHEMBL162803

CCCCCCCCCCCCc1ccccc1OP(=S)([S-])Oc1ccccc1CCCCCCCCCCCC.CCCCCCCCCCCCc1ccccc1OP(=S)([S-])Oc1ccccc1CCCCCCCCCCCC.[Zn+2]

nearest known ligand 0.55

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
THRA P10827 1/20 0.55
THRB P10828 1/20 0.55
LIPG Q9Y5X9 1/20 0.45
ALOX5 P09917 1/20 0.44
PTGS2 P35354 1/20 0.44
PPARA Q07869 3/20 0.44
PPARG P37231 2/20 0.44
NR1H2 P55055 1/20 0.38
NR1H3 Q13133 1/20 0.38
LTB4R Q15722 1/20 0.36
LTB4R2 Q9NPC1 1/20 0.36
BID P55957 3/20 0.36
MCL1 Q07820 3/20 0.36
BCL2L1 Q07817 2/20 0.36
BAK1 Q16611 2/20 0.36
KAT8 Q9H7Z6 2/20 0.36
EP300 Q09472 1/20 0.36
KAT2A Q92830 1/20 0.36
KAT2B Q92831 1/20 0.36
KAT5 Q92993 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Zinc Ion SCHEMBL30830367 1.00 THRA (0.55) THRATHRBLIPGALOX5PTGS2
Zinc Ion SCHEMBL9442241 1.00 THRA (0.55) THRATHRBLIPGALOX5PTGS2
Zinc Ion SCHEMBL159097 1.00 THRA (0.55) THRATHRBLIPGALOX5PTGS2
Zinc Ion SCHEMBL8037336 1.00 THRA (0.55) THRATHRBLIPGALOX5PTGS2
SCHEMBL2379852 0.97 THRA (0.55) THRATHRBLIPGALOX5PTGS2
SCHEMBL4019156 0.97 THRA (0.55) THRATHRBLIPGALOX5PTGS2
SCHEMBL27128037 0.97 THRA (0.55) THRATHRBLIPGALOX5PTGS2
SCHEMBL486877 0.95 THRA (0.53) THRATHRBLIPGALOX5PTGS2
SCHEMBL8661503 0.94 THRA (0.56) THRATHRBLIPGALOX5PTGS2
SCHEMBL2380466 0.94 THRA (0.56) THRATHRBLIPGALOX5PTGS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 165 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2197994-A1 LUBRICANTS THAT DECREASE MICROPITTING FOR INDUSTRIAL GEARS The Lubrizol Corporation (US) 2010-06-23 EP claimed
US-20090093384-A1 Lubricants That Decrease Micropitting for Industrial Gears THE LUBRIZOL CORPORATION (US) 2009-04-09 US claimed
WO-2009045979-A1 LUBRICANTS THAT DECREASE MICROPITTING FOR INDUSTRIAL GEARS THE LUBRIZOL CORPORATION (US) 2009-04-09 WO claimed
US-4456539-A ANTIOXIDANTS MOBIL OIL CORPORATION (US) 1984-06-26 US claimed
US-20260092232-A1 LOW-ASH LUBRICATING COMPOSITIONS AFTON CHEMICAL CORP (US) 2026-04-02 US disclosed
EP-4717752-A1 LOW-ASH LUBRICATING COMPOSITIONS Afton Chemical Corporation (US) 2026-04-01 EP disclosed
EP-4655365-A1 LUBRICATING COMPOSITION WITH PHENOLIC ANTIOXIDANT AND LOW ACTIVE SULFUR The Lubrizol Corporation (US) 2025-12-03 EP disclosed
US-12480066-B2 Antiwear systems for improved wear in medium and/or heavy duty diesel engines AFTON CHEMICAL CORPORATION 2025-11-25 US disclosed
US-12460150-B1 Low-ash lubricating compositions AFTON CHEMICAL CORPORATION 2025-11-04 US disclosed
WO-2025128086-A1 LOW ASH LUBRICATING COMPOSITION FOR IMPROVED PISTON CLEANLINESS IN MOTORCYCLE APPLICATIONS AFTON CHEMICAL CORPORATION (US) 2025-06-19 WO disclosed
EP-4410934-B1 DISPERSANT AND DETERGENT SYSTEMS FOR IMPROVED MOTOR OIL PERFORMANCE AFTON CHEMICAL CORP (US) 2025-03-12 EP disclosed
EP-4520807-A1 DETERGENT AND DISPERSANT SYSTEMS FOR IMPROVED STEEL PISTON CLEANLINESS IN HEAVY DUTY LUBRICANTS Afton Chemical Corporation (US) 2025-03-12 EP disclosed
EP-0638633-B1 Reclamation of used lubricating oil TEXACO DEVELOPMENT CORP (US) 2000-03-22 EP disclosed
US-5447628-A Reconstituting lubricating oil TEXACO INC. (US) 1995-09-05 US disclosed
EP-0638633-A1 Reclamation of used lubricating oil TEXACO DEVELOPMENT CORPORATION (US) 1995-02-15 EP disclosed
US-5306419-A Used lubricating oil reclaiming TEXACO INC. (US) 1994-04-26 US disclosed
EP-0407977-B1 LUBRICATING OIL COMPOSITION IDEMITSU KOSAN COMPANY LIMITED (JP) 1993-04-28 EP disclosed
US-5198129-A Unsaturated Higher Alcohol IDEMITSU KOSAN CO., LTD. (JP) 1993-03-30 US disclosed
EP-0407977-A1 Lubricating oil composition IDEMITSU KOSAN COMPANY LIMITED (JP) 1991-01-16 EP disclosed
US-4456539-A ANTIOXIDANTS MOBIL OIL CORPORATION (US) 1984-06-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260092232-A1 LOW-ASH LUBRICATING COMPOSITIONS SUPT16H, SOST, ATR THRA 1556/4885THRB 1663/4885LIPG 1266/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.