⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1140837 | 0.73 | — | — | |
| SCHEMBL1828301 | 0.71 | THRB (0.35) | — | |
| SCHEMBL30643915 | 0.64 | — | — | |
| SCHEMBL7268029 | 0.64 | — | — | |
| SCHEMBL6368378 | 0.62 | — | — | |
| SCHEMBL8057392 | 0.62 | — | — | |
| SCHEMBL2927552 | 0.60 | — | — | |
| SCHEMBL3475481 | 0.58 | — | — | |
| SCHEMBL21112809 | 0.57 | — | — | |
| SCHEMBL4599390 | 0.57 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10241234-B2 | Silicone hydrogel soft contact lens having wettable surface | HOYA CORPORATION (JP) | 2019-03-26 | — | — | US | disclosed |
| EP-2840431-B1 | SILICONE HYDROGEL SOFT CONTACT LENS HAVING WETTABLE SURFACE | HOYA CORP (JP) | 2016-09-07 | — | — | EP | disclosed |
| EP-2840431-A1 | SILICONE HYDROGEL SOFT CONTACT LENS HAVING WETTABLE SURFACE | HOYA CORPORATION (JP) | 2015-02-25 | — | — | EP | disclosed |
| US-20140362339-A1 | SILICONE HYDROGEL SOFT CONTACT LENS HAVING WETTABLE SURFACE | HOYA CORPORATION (JP) | 2014-12-11 | — | — | US | disclosed |