SCHEMBL16280654

SCHEMBL16280654

N[C@@H](CNc1cc(-c2ccc(Cl)c(CF)c2)ncn1)c1ccccc1

nearest known ligand 0.56

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
FAAH O00519 20/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9898876 0.88 FAAH (0.58) FAAH
SCHEMBL16280657 0.85 FAAH (0.62) FAAH
SCHEMBL9899604 0.84 FAAH (0.78) FAAH
SCHEMBL9925709 0.84 FAAH (0.60) FAAH
SCHEMBL9925711 0.84 FAAH (0.60) FAAH
SCHEMBL9900348 0.83 FAAH (0.74) FAAH
SCHEMBL9899296 0.82 FAAH (0.78) FAAH
SCHEMBL9899425 0.82 FAAH (0.78) FAAH
SCHEMBL9899680 0.81 FAAH (0.75) FAAH
SCHEMBL9925773 0.81 FAAH (0.56) FAAH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8906914-B2 Ethylene diamine modulators of fatty acid hydrolase JANSSEN PHARMACEUTICA NV (BE) 2014-12-09 US disclosed