SCHEMBL16280657

SCHEMBL16280657

CCOc1ccc(-c2cc(NC[C@H](N)c3ccccc3)ncn2)cc1CF

nearest known ligand 0.62

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
FAAH O00519 20/20 0.62

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9925715 0.89 FAAH (0.78) FAAH
SCHEMBL9898508 0.86 FAAH (0.79) FAAH
SCHEMBL16280654 0.85 FAAH (0.56) FAAH
SCHEMBL9899427 0.83 FAAH (0.76) FAAH
SCHEMBL9899198 0.82 FAAH (0.64) FAAH
SCHEMBL9925712 0.79 FAAH (0.60) FAAH
SCHEMBL9925713 0.78 FAAH (0.74) FAAH
SCHEMBL9899538 0.78 FAAH (0.79) FAAH
SCHEMBL9899902 0.78 FAAH (0.79) FAAH
SCHEMBL9899441 0.78 FAAH (0.76) FAAH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8906914-B2 Ethylene diamine modulators of fatty acid hydrolase JANSSEN PHARMACEUTICA NV (BE) 2014-12-09 US disclosed