Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 5/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.32 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.32 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27347790 | 1.00 | LMNA (0.48) | LMNAMCL1POLBMEN1KMT2A | |
| SCHEMBL22787027 | 0.97 | LMNA (0.50) | LMNAMCL1POLBMEN1KMT2A | |
| SCHEMBL15082734 | 0.91 | ALDH1A1 (0.45) | LMNAMCL1POLBKMT2ATSHR | |
| SCHEMBL13449837 | 0.91 | LMNA (0.41) | LMNAMCL1POLBMEN1KMT2A | |
| SCHEMBL15763876 | 0.91 | ALDH1A1 (0.45) | LMNAMCL1POLBKMT2ATSHR | |
| SCHEMBL24408071 | 0.91 | LMNA (0.41) | LMNAMCL1POLBMEN1KMT2A | |
| SCHEMBL16298991 | 0.91 | LMNA (0.41) | LMNAMCL1POLBMEN1KMT2A | |
| SCHEMBL22266339 | 0.91 | MEN1 (0.48) | LMNAMCL1POLBMEN1KMT2A | |
| SCHEMBL24285433 | 0.91 | LMNA (0.41) | LMNAMCL1POLBMEN1KMT2A | |
| SCHEMBL13598106 | 0.91 | LMNA (0.41) | LMNAMCL1POLBMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9012603-B2 | Peptides that block the binding of IgG to FcRn | BIOGEN IDEC HEMOPHILIA INC. (US) | 2015-04-21 | — | — | US | disclosed |
| US-8906844-B2 | Immunomodulatory peptides | BIOGEN IDEC HEMOPHILIA INC. (US) | 2014-12-09 | — | — | US | disclosed |