Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22433099 | 0.78 | — | — | |
| SCHEMBL16281180 | 0.77 | ALDH1A1 (0.35) | ALDH1A1TSHRTDP1 | |
| SCHEMBL824974 | 0.71 | — | — | |
| SCHEMBL19822023 | 0.70 | ALDH1A1 (0.32) | ALDH1A1TSHRTDP1 | |
| SCHEMBL3217513 | 0.69 | LMNA (0.40) | ALDH1A1TSHRTDP1 | |
| SCHEMBL12632074 | 0.69 | TSHR (0.39) | ALDH1A1TSHRTDP1 | |
| SCHEMBL13832509 | 0.69 | — | — | |
| SCHEMBL23179734 | 0.68 | MAPK1 (0.44) | — | |
| SCHEMBL27271766 | 0.67 | ALDH1A1 (0.38) | ALDH1A1TSHRTDP1 | |
| SCHEMBL21000571 | 0.65 | ALDH1A1 (0.37) | ALDH1A1TSHRTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8906853-B2 | [N-Me-4-hydroxyleucine]-9-cyclosporin analogues for treatment and prevention of hepatitis C infection | ENANTA PHARMACEUTICALS, INC. (US) | 2014-12-09 | — | — | US | disclosed |