SCHEMBL14822265

SCHEMBL14822265

CC1(C)c2ccccc2-c2cc3c4cc(-c5ccc6c(c5)c5ccccc5n6-c5ccccc5)ccc4n(-c4ccc5c(c4)c4ccccc4n5-c4ccccc4)c3cc21

nearest known ligand 0.41

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.41
ATM Q13315 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
HDAC4 P56524 1/20 0.34
PTGER4 P35408 1/20 0.33
PGR P06401 1/20 0.33
TSPO P30536 1/20 0.32
RAC2 P15153 1/20 0.31
RAC3 P60763 1/20 0.31
CDC42 P60953 1/20 0.31
RAC1 P63000 1/20 0.31
EDNRB P24530 1/20 0.30
EDNRA P25101 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14960776 1.00 KDM4E (0.41) KDM4EATML3MBTL1HDAC4PTGER4
SCHEMBL14822256 1.00 KDM4E (0.41) KDM4EATML3MBTL1HDAC4PTGER4
SCHEMBL16282979 0.98 KDM4E (0.39) KDM4EATML3MBTL1HDAC4PTGER4
SCHEMBL14822608 0.98 L3MBTL1 (0.39) KDM4EATML3MBTL1HDAC4PTGER4
SCHEMBL14822431 0.98 L3MBTL1 (0.39) KDM4EATML3MBTL1HDAC4PTGER4
SCHEMBL16076388 0.97 KDM4E (0.38) KDM4EATML3MBTL1HDAC4PTGER4
SCHEMBL16076396 0.97 KDM4E (0.38) KDM4EATML3MBTL1HDAC4PTGER4
SCHEMBL21124994 0.97 KDM4E (0.38) KDM4EATML3MBTL1HDAC4PTGER4
SCHEMBL14886395 0.97 KDM4E (0.38) KDM4EATML3MBTL1HDAC4PTGER4
SCHEMBL16076422 0.97 KDM4E (0.38) KDM4EATML3MBTL1HDAC4PTGER4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11917903-B2 Metal complexes UDC IRELAND LIMITED (IE) 2024-02-27 US disclosed
US-11917903-B2 Metal complexes UDC IRELAND LIMITED (IE) 2024-02-27 US disclosed
US-11322696-B2 Metal complexes MERCK PATENT GMBH (DE) 2022-05-03 US disclosed
US-11145828-B2 Metal complexes MERCK PATENT GMBH (DE) 2021-10-12 US disclosed
US-11136343-B2 Binuclear metal complexes for use as emitters in organic electroluminescent devices MERCK PATENT GMBH (DE) 2021-10-05 US disclosed
US-20210111345-A1 METAL COMPLEXES UDC IRELAND LIMITED (IE) 2021-04-15 US disclosed
WO-2021037401-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2021-03-04 WO disclosed
US-10889604-B2 Binuclear and trinuclear metal complexes composed of two inter-linked tripodal hexadentate ligands for use in electroluminescent devices MERCK PATENT GMBH 2021-01-12 US disclosed
EP-3526228-B1 METAL COMPLEXES MERCK PATENT GMBH (DE) 2020-11-25 EP disclosed
EP-3526226-B1 METAL COMPLEXES MERCK PATENT GMBH (DE) 2020-07-22 EP disclosed
WO-2018069273-A1 METAL COMPLEXES MERCK PATENT GMBH (DE) 2018-04-19 WO disclosed
WO-2018069197-A1 METAL COMPLEXES MERCK PATENT GMBH (DE) 2018-04-19 WO disclosed
WO-2018069196-A1 BINUCLEAR METAL COMPLEXES AND ELECTRONIC DEVICES, IN PARTICULAR ORGANIC ELECTROLUMINESCENT DEVICES CONTAINING SAID METAL COMPLEXES MERCK PATENT GMBH (DE) 2018-04-19 WO disclosed
WO-2018054798-A1 BINUCLEAR METAL COMPLEXES FOR USE AS EMITTERS IN ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2018-03-29 WO disclosed
WO-2018041769-A1 BINUCLEAR AND TRINUCLEAR METAL COMPLEXES COMPOSED OF TWO INTER-LINKED TRIPODAL HEXADENTATE LIGANDS FOR USE IN ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2018-03-08 WO disclosed
US-9818948-B2 Carbazole derivatives for organic electroluminescence devices MERCK PATENT GMBH (DE) 2017-11-14 US disclosed
US-9818948-B2 Carbazole derivatives for organic electroluminescence devices MERCK PATENT GMBH (DE) 2017-11-14 US disclosed
US-20140225046-A1 CARBAZOLE DERIVATIVES FOR ORGANIC ELECTROLUMINESCENCE DEVICES MERCK PATENT GMBH (DE) 2014-08-14 US disclosed
US-20140225046-A1 CARBAZOLE DERIVATIVES FOR ORGANIC ELECTROLUMINESCENCE DEVICES MERCK PATENT GMBH (DE) 2014-08-14 US disclosed
WO-2013041176-A1 CARBAZOLE DERIVATIVES FOR ORGANIC ELECTROLUMINESCENCE DEVICES MERCK PATENT GMBH (DE) 2013-03-28 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11145828-B2 Metal complexes AP1M1, AP2M1, AP3M1 KDM4E 3877/4885ATM 4131/4885L3MBTL1 3031/4885
US-10889604-B2 Binuclear and trinuclear metal complexes composed of two inter-linked tripodal hexadentate ligands for use in electroluminescent devices PARN, PUF60, PARG KDM4E 4048/4885ATM 3697/4885L3MBTL1 1520/4885
US-20210111345-A1 METAL COMPLEXES NCLN, BICRA, AP3M1 KDM4E 3870/4885ATM 3416/4885L3MBTL1 2532/4885
US-11322696-B2 Metal complexes AP1M1, AP3M1, AP2M1 KDM4E 4376/4885ATM 4372/4885L3MBTL1 3543/4885
US-11136343-B2 Binuclear metal complexes for use as emitters in organic electroluminescent devices AP2M1, MCU, AP3M1 KDM4E 4613/4885ATM 4246/4885L3MBTL1 2504/4885
US-11917903-B2 Metal complexes NCLN, BICRA, AP3M1 KDM4E 3870/4885ATM 3416/4885L3MBTL1 2532/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.