SCHEMBL16283262

SCHEMBL16283262

c1ccc(-n2c3ccccc3c3cc(-c4ccc5c6c4ccc4cccc(c46)n5-c4ccc5c(c4)c4ccccc4n5-c4ccccc4)ccc32)cc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.43
ATM Q13315 1/20 0.43
L3MBTL1 Q9Y468 1/20 0.43
PTGER4 P35408 1/20 0.34
HDAC4 P56524 1/20 0.33
PTGES O14684 1/20 0.32
JAK2 O60674 1/20 0.32
JAK3 P52333 1/20 0.32
EDNRB P24530 1/20 0.31
EDNRA P25101 1/20 0.31
ERBB2 P04626 1/20 0.31
CYP1A2 P05177 1/20 0.31
FYN P06241 1/20 0.31
MAOA P21397 1/20 0.31
ACHE P22303 1/20 0.31
AHR P35869 1/20 0.31
KMT2A Q03164 1/20 0.30
IL1R1 P14778 1/20 0.30
ALDH1A1 P00352 1/20 0.30
TSHR P16473 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16283323 1.00 KDM4E (0.43) KDM4EATML3MBTL1PTGER4HDAC4
SCHEMBL16283325 1.00 KDM4E (0.43) KDM4EATML3MBTL1PTGER4HDAC4
SCHEMBL16283270 0.98 L3MBTL1 (0.45) KDM4EATML3MBTL1PTGER4HDAC4
SCHEMBL16283342 0.96 KDM4E (0.42) KDM4EATML3MBTL1PTGER4HDAC4
SCHEMBL16283339 0.96 KDM4E (0.42) KDM4EATML3MBTL1PTGER4HDAC4
SCHEMBL16283276 0.96 KDM4E (0.42) KDM4EATML3MBTL1PTGER4HDAC4
SCHEMBL16283221 0.96 L3MBTL1 (0.46) KDM4EATML3MBTL1PTGER4HDAC4
SCHEMBL17562181 0.95 KDM4E (0.41) KDM4EATML3MBTL1PTGER4HDAC4
SCHEMBL16283278 0.93 L3MBTL1 (0.45) KDM4EATML3MBTL1PTGER4HDAC4
SCHEMBL16369536 0.93 KDM4E (0.47) KDM4EATML3MBTL1HDAC4JAK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9537108-B2 Heterocyclic compound and organic light-emitting device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2017-01-03 US disclosed
US-20140361267-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2014-12-11 US disclosed
US-20140361267-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2014-12-11 US disclosed