SCHEMBL16283276

SCHEMBL16283276

c1ccc(-n2c3ccccc3c3cc(-n4c5cccc6ccc7c(-c8ccc9c%10ccccc%10n(-c%10ccccc%10)c9c8)ccc4c7c65)ccc32)cc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.42
ATM Q13315 1/20 0.42
L3MBTL1 Q9Y468 1/20 0.42
HDAC4 P56524 1/20 0.32
PTGER4 P35408 1/20 0.31
JAK2 O60674 1/20 0.31
JAK3 P52333 1/20 0.31
F2 P00734 1/20 0.31
F10 P00742 1/20 0.31
PRSS1 P07477 1/20 0.31
EDNRB P24530 1/20 0.31
EDNRA P25101 1/20 0.31
MAT2A P31153 1/20 0.31
NTSR1 P30989 1/20 0.31
ALDH1A1 P00352 2/20 0.30
MAPT P10636 1/20 0.30
MAPK1 P28482 1/20 0.30
NPSR1 Q6W5P4 1/20 0.30
RXFP1 Q9HBX9 1/20 0.30
ERBB2 P04626 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16283339 1.00 KDM4E (0.42) KDM4EATML3MBTL1HDAC4PTGER4
SCHEMBL16283342 1.00 KDM4E (0.42) KDM4EATML3MBTL1HDAC4PTGER4
SCHEMBL16283323 0.96 KDM4E (0.43) KDM4EATML3MBTL1HDAC4PTGER4
SCHEMBL16283262 0.96 KDM4E (0.43) KDM4EATML3MBTL1HDAC4PTGER4
SCHEMBL16283325 0.96 KDM4E (0.43) KDM4EATML3MBTL1HDAC4PTGER4
SCHEMBL16283278 0.96 L3MBTL1 (0.45) KDM4EATML3MBTL1HDAC4PTGER4
SCHEMBL16283266 0.95 L3MBTL1 (0.46) KDM4EATML3MBTL1HDAC4PTGER4
SCHEMBL16283270 0.94 L3MBTL1 (0.45) KDM4EATML3MBTL1HDAC4PTGER4
SCHEMBL16283221 0.93 L3MBTL1 (0.46) KDM4EATML3MBTL1HDAC4PTGER4
SCHEMBL17562181 0.92 KDM4E (0.41) KDM4EATML3MBTL1HDAC4PTGER4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9537108-B2 Heterocyclic compound and organic light-emitting device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2017-01-03 US disclosed
US-20140361267-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2014-12-11 US disclosed
US-20140361267-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2014-12-11 US disclosed