Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 4/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | APAF1 | O14727 | 1/20 | 0.38 |
| ▸ | CASP3 | P42574 | 1/20 | 0.38 |
| ▸ | CASP6 | P55212 | 1/20 | 0.38 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.38 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.38 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 4/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | JAK3 | P52333 | 2/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | AKT2 | P31751 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1629504 | 0.98 | ACACB (0.45) | ACACBLMNAALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL10074122 | 0.98 | ACACB (0.45) | ACACBLMNAALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL10074499 | 0.87 | ACACB (0.44) | ACACBLMNAALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL10074502 | 0.86 | ACACB (0.43) | ACACBLMNAALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL10074500 | 0.86 | ACACB (0.43) | ACACBLMNAALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL19725055 | 0.80 | ACACB (0.48) | ACACBALDH1A1MEN1KMT2A | |
| SCHEMBL393595 | 0.80 | ACACB (0.36) | ACACBLMNAALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL16190524 | 0.79 | ACACB (0.49) | ACACBMEN1KMT2A | |
| SCHEMBL83873 | 0.79 | LMNA (0.38) | ACACBLMNAALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL82724 | 0.79 | LMNA (0.38) | ACACBLMNAALDH1A1SMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120088914-A1 | PRODUCTION METHOD OF PYRIMIDINE COMPOUNDS | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-04-12 | — | — | US | disclosed |
| US-8101753-B2 | Production method of pyrimidine compounds | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-01-24 | — | — | US | disclosed |
| US-20080039445-A1 | PRODUCTION METHOD OF PYRIMIDINE COMPOUNDS | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2008-02-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120088914-A1 | PRODUCTION METHOD OF PYRIMIDINE COMPOUNDS | DPYD, DHFR, DHODH | ACACB 426/4885LMNA 4693/4885ALDH1A1 61/4885 |
| US-20080039445-A1 | PRODUCTION METHOD OF PYRIMIDINE COMPOUNDS | DPYD, DHFR, DHODH | ACACB 426/4885LMNA 4693/4885ALDH1A1 61/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.