SCHEMBL1628386

SCHEMBL1628386

COC(=O)OC1CCC=CCCC1

nearest known ligand 0.38

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
EPHX1 P07099 2/20 0.38
CYP19A1 P11511 2/20 0.34
SMN1; SMN2 Q16637 3/20 0.33
NPC1 O15118 2/20 0.33
RAB9A P51151 2/20 0.33
TSHR P16473 2/20 0.33
MAPT P10636 1/20 0.33
LMNA P02545 1/20 0.33
TP53 P04637 1/20 0.33
NAAA Q02083 2/20 0.33
ACACB O00763 3/20 0.32
TDP1 Q9NUW8 1/20 0.32
HTT P42858 1/20 0.32
CYP3A4 P08684 1/20 0.31
CYP2C19 P33261 1/20 0.31
PTGS1 P23219 1/20 0.31
PTGS2 P35354 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL756915 1.00 EPHX1 (0.38) EPHX1CYP19A1SMN1; SMN2NPC1RAB9A
SCHEMBL31490424 1.00 EPHX1 (0.38) EPHX1CYP19A1SMN1; SMN2NPC1RAB9A
SCHEMBL3682781 0.94 EPHX1 (0.37) EPHX1CYP19A1SMN1; SMN2NPC1RAB9A
SCHEMBL3678106 0.87 LMNA (0.36) EPHX1CYP19A1SMN1; SMN2TSHRLMNA
SCHEMBL5430000 0.85 SMN1; SMN2 (0.40) EPHX1SMN1; SMN2NPC1RAB9ATSHR
SCHEMBL698655 0.83
SCHEMBL305953 0.83 EPHX1 (0.50) EPHX1CYP19A1SMN1; SMN2NPC1RAB9A
SCHEMBL10344338 0.83 EPHX1 (0.45) EPHX1CYP19A1SMN1; SMN2NPC1RAB9A
SCHEMBL4265853 0.82 EPHX1 (0.37) EPHX1CYP19A1SMN1; SMN2NPC1RAB9A
SCHEMBL3673877 0.81 EPHX1 (0.36) EPHX1CYP19A1SMN1; SMN2NPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 193 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240010954-A1 LAUNDRY DETERGENT COMPOSITION CONTAINING GRAFT COPOLYMER AND BENEFIT AGENT THE PROCTER & GAMBLE COMPANY 2024-01-11 US claimed
EP-2708592-B2 Fabric care composition PROCTER & GAMBLE (US) 2022-03-16 EP claimed
US-10552557-B2 Freshening compositions and devices comprising same THE PROCTER & GAMBLE COMPANY (US) 2020-02-04 US claimed
US-20190155975-A9 Antiperspirant and Deodorant Compositions Comprising Malodor Reduction Compositions THE PROCTER & GAMBLE COMPANY 2019-05-23 US claimed
EP-2708592-B1 Fabric care composition PROCTER & GAMBLE (US) 2019-02-13 EP claimed
US-20180296719-A1 AIR FRESHENING DEVICE UTILIZING A SOLID-FORM COMPOSITION AND A METHOD OF FRESHENING THE AIR THE PROCTER & GAMBLE COMPANY 2018-10-18 US claimed
WO-2018145219-A1 PHARMACEUTICAL COMPOSITION FOR PREVENTING AND TREATING ADDICTIONS BY MEANS OF AVERSIVE COUNTERCONDITIONING SERANI MOSTAZAL JORGE (CL) 2018-08-16 WO claimed
EP-3309245-A1 ENCAPSULATES The Procter & Gamble Company (US) 2018-04-18 EP claimed
US-20180066210-A1 DELIVERY SYSTEMS COMPRISING MALODOR REDUCTION COMPOSITIONS PROCTER & GAMBLE (US) 2018-03-08 US claimed
EP-2512406-B1 PERFUMES AND PERFUME ENCAPSULATES PROCTER & GAMBLE (US) 2018-01-24 EP claimed
US-20130336911-A1 MOC Compositions GIVAUDAN SA (CH) 2013-12-19 US claimed
EP-2652102-A1 MOC COMPOSITIONS Givaudan SA (CH) 2013-10-23 EP claimed
EP-2512406-A1 PERFUMES AND PERFUME ENCAPSULATES The Procter & Gamble Company (US) 2012-10-24 EP claimed
WO-2012080235-A1 MOC COMPOSITIONS GIVAUDAN SA (CH) 2012-06-21 WO claimed
US-20030036489-A1 Consumable composition comprising perfumed particles and article containing the same THE PROCTER & GAMBLE COMPANY 2003-02-20 US claimed
WO-2002090479-A1 PERFUMED PARTICLES AND ARTICLES CONTAINING THE SAME THE PROCTER & GAMBLE COMPANY (US) 2002-11-14 WO claimed
WO-2002090481-A1 COMPOSITIONS AND ARTICLES FOR EFFECTIVE DEPOSITION OF PERFUME THE PROCTER & GAMBLE COMPANY (US) 2002-11-14 WO claimed
US-6162454-A Insect repellent article providing low contact wetness THE PROCTER & GAMBLE COMPANY (US) 2000-12-19 US claimed
US-5798385-A PARA-ISOPROPYLCYCLOHEXANOL, 3,7-DIMETHYL-2,6-OCTADIEN-1-AL, 5,9-DIMETHYL-4,8-DECADIENAL, P-MENTHA-1,8-DIENE, O-METHYL-BETAPHENYLETHYL ALCOHOL AND 4-CYCLOOCTENYL METHYL CARBONATE INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 1998-08-25 US claimed
US-5576011-A Method for repelling insects using cyclic organic alcohol or carbonates and device useful in carrying out such method INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 1996-11-19 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10552557-B2 Freshening compositions and devices comprising same CFD, C5, PDE6G EPHX1 2234/4885CYP19A1 2710/4885SMN1; SMN2 1694/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.