Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLO1 | Q04760 | 3/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 11/20 | 0.62 |
| ▸ | MEN1 | O00255 | 10/20 | 0.62 |
| ▸ | MAPT | P10636 | 9/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 5/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.54 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.48 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.47 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.47 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11812896 | 0.94 | KMT2A (0.70) | GLO1KMT2AMEN1MAPTKDM4E | |
| SCHEMBL7379346 | 0.88 | GLO1 (0.68) | GLO1KMT2AMEN1MAPTKDM4E | |
| SCHEMBL7379349 | 0.88 | GLO1 (0.68) | GLO1KMT2AMEN1MAPTKDM4E | |
| SCHEMBL2424030 | 0.86 | GLO1 (0.65) | GLO1KMT2AMEN1MAPTKDM4E | |
| SCHEMBL16285261 | 0.86 | GLO1 (0.65) | GLO1KMT2AMEN1MAPTKDM4E | |
| SCHEMBL15026370 | 0.86 | GLO1 (0.65) | GLO1KMT2AMEN1MAPTKDM4E | |
| SCHEMBL2424031 | 0.86 | GLO1 (0.65) | GLO1KMT2AMEN1MAPTKDM4E | |
| SCHEMBL21065588 | 0.85 | KMT2A (0.53) | GLO1KMT2AMEN1MAPTKDM4E | |
| SCHEMBL14113061 | 0.85 | KMT2A (0.53) | GLO1KMT2AMEN1MAPTKDM4E | |
| SCHEMBL7271180 | 0.85 | GLO1 (0.64) | GLO1KMT2AMEN1MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9284330-B2 | 1,4-dihydro-naphthyridine derivative and pharmaceutical composition and use thereof | JIANGSU SIMOVAY PHARMACEUTICAL CO., LTD. (CN) | 2016-03-15 | — | — | US | disclosed |
| US-20140364443-A1 | 1,4-DIHYDRO-NAPHTHYRIDINE DERIVATIVE AND PHARMACEUTICAL COMPOSITION AND USE THEREOF | JIANGSU SIMOVAY PHARMACEUTICAL CO., LTD. (CN) | 2014-12-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140364443-A1 | 1,4-DIHYDRO-NAPHTHYRIDINE DERIVATIVE AND PHARMACEUTICAL COMPOSITION AND USE THEREOF | ACHE, BACE1, CACNA1D | GLO1 2229/4885KMT2A 3555/4885MEN1 2207/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.