SCHEMBL16286804

SCHEMBL16286804

C=CC(=O)OCCCCCCCC[Si](C)(C)OCC

nearest known ligand 0.59

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
TSHR P16473 9/20 0.59
ALDH1A1 P00352 4/20 0.59
CYP3A4 P08684 2/20 0.59
HPGD P15428 1/20 0.54
TP53 P04637 3/20 0.42
HIF1A Q16665 3/20 0.42
HSD17B10 Q99714 1/20 0.42
THRB P10828 2/20 0.40
HCAR2 Q8TDS4 3/20 0.38
ATM Q13315 1/20 0.37
MAPK1 P28482 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
ACHE P22303 4/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16537305 1.00 TSHR (0.59) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL29965163 1.00 TSHR (0.59) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL29947959 1.00 TSHR (0.59) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL16536923 0.98 TSHR (0.56) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL107693 0.94 TSHR (0.58) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL29965478 0.88 TSHR (0.60) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL16286756 0.88 TSHR (0.59) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL29737735 0.88 TSHR (0.59) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL29737752 0.88 TSHR (0.59) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL21402795 0.88 TSHR (0.59) TSHRALDH1A1CYP3A4HPGDTP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4074774-A2 TIRE Sumitomo Rubber Industries, Ltd. (JP) 2022-10-19 EP disclosed
WO-2022202005-A1 PHOTOCURABLE COMPOSITION FOR FILM FORMATION 日産化学株式会社 2022-09-29 WO disclosed
EP-4056639-A1 ELASTOMER COMPOSITION AND TIRE Sumitomo Rubber Industries, Ltd. (JP) 2022-09-14 EP disclosed
CN-109666399-A Hardcoat film constituent and hardcoat film 奇美实业股份有限公司 2019-04-23 CN disclosed
CN-104080815-B Solidification compound and its purposes SHOWA DENKO KABUSHIKI KAISHA (JP) 2016-03-02 CN disclosed
US-9109072-B2 Curable composition and uses thereof SHOWA DENKO K.K. (JP) 2015-08-18 US disclosed
US-20140378571-A1 CURABLE COMPOSITION AND USES THEREOF SHOWA DENKO K.K. (JP) 2014-12-25 US disclosed
EP-2813521-A1 CURABLE COMPOSITION AND APPLICATION THEREFOR Showa Denko K.K. (JP) 2014-12-17 EP disclosed
CN-104080815-A Curable composition and application therefor SHOWA DENKO KK 2014-10-01 CN disclosed