SCHEMBL107693

SCHEMBL107693

C=CC(=O)OCCC[Si](C)(C)OCC

nearest known ligand 0.58

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
TSHR P16473 7/20 0.58
HPGD P15428 1/20 0.58
ALDH1A1 P00352 4/20 0.53
CYP3A4 P08684 2/20 0.53
TP53 P04637 3/20 0.44
HIF1A Q16665 3/20 0.44
HSD17B10 Q99714 1/20 0.44
THRB P10828 2/20 0.41
ATM Q13315 1/20 0.39
MAPK1 P28482 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
HCAR2 Q8TDS4 4/20 0.35
MAPT P10636 1/20 0.31
RAB9A P51151 1/20 0.31
NPSR1 Q6W5P4 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16536923 0.95 TSHR (0.56) TSHRHPGDALDH1A1CYP3A4TP53
SCHEMBL29965163 0.94 TSHR (0.59) TSHRHPGDALDH1A1CYP3A4TP53
SCHEMBL16537305 0.94 TSHR (0.59) TSHRHPGDALDH1A1CYP3A4TP53
SCHEMBL16286804 0.94 TSHR (0.59) TSHRHPGDALDH1A1CYP3A4TP53
SCHEMBL29947959 0.94 TSHR (0.59) TSHRHPGDALDH1A1CYP3A4TP53
SCHEMBL673300 0.90 TSHR (0.52) TSHRHPGDALDH1A1CYP3A4TP53
SCHEMBL3440898 0.89 TSHR (0.61) TSHRHPGDALDH1A1CYP3A4TP53
SCHEMBL22115841 0.87 TSHR (0.69) TSHRHPGDALDH1A1CYP3A4TP53
SCHEMBL108297 0.87 TSHR (0.58) TSHRHPGDALDH1A1CYP3A4TP53
SCHEMBL8899031 0.87 TSHR (0.58) TSHRHPGDALDH1A1CYP3A4TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 588 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4326795-B1 POLYMERIZATION OF A SILANE-MODIFIED POLYMER, WHICH IS PRODUCED BY MEANS OF A RADICAL CHAIN POLYMERIZATION, IN A POLYOL OR IN A PREPOLYMER WITH TERMINAL ISOCYANATE GROUPS, AND USE THEREOF IN POLYURETHANE FORMULATIONS FOLLMANN GMBH & CO KG (DE) 2026-02-25 EP claimed
EP-4605483-A1 FREE-RADICAL POLYMERISATION OF UV-CROSSLINKING SILANE ACRYLATES IN AN ISOCYANATE-CONTAINING POLYURETHANE MATRIX Follmann GmbH & Co. KG (DE) 2025-08-27 EP claimed
US-20240240069-A1 POLYMERIZATION OF A SILANE-MODIFIED POLYMER, WHICH IS PRODUCED BY MEANS OF A RADICAL CHAIN POLYMERIZATION, IN A POLYOL OR IN A PREPOLYMER WITH TERMINAL ISOCYANATE GROUPS, AND USE THEREOF IN POLYURETHANE FORMULATIONS FOLLMANN GMBH & CO. KG (DE) 2024-07-18 US claimed
WO-2024083887-A1 FREE-RADICAL POLYMERISATION OF UV-CROSSLINKING SILANE ACRYLATES IN AN ISOCYANATE-CONTAINING POLYURETHANE MATRIX FOLLMANN GMBH & CO. KG (DE) 2024-04-25 WO claimed
CN-114762822-B Composite adsorption film for water treatment and preparation method and application thereof 神华神东煤炭集团有限责任公司 2024-03-15 CN claimed
EP-4326795-A1 POLYMERIZATION OF A SILANE-MODIFIED POLYMER, WHICH IS PRODUCED BY MEANS OF A RADICAL CHAIN POLYMERIZATION, IN A POLYOL OR IN A PREPOLYMER WITH TERMINAL ISOCYANATE GROUPS, AND USE THEREOF IN POLYURETHANE FORMULATIONS Follmann GmbH & Co. KG (DE) 2024-02-28 EP claimed
CN-117396530-A Polymerization of silane-modified polymers produced by free-radical chain polymerization in polyols or prepolymers having terminal isocyanate groups and their use in polyurethane formulations 福漫有限责任两合公司 2024-01-12 CN claimed
US-11725136-B2 Process for manufacturing light absorbing polymer matrix ESSILOR INTERNATIONAL (FR) 2023-08-15 US claimed
EP-4035649-B1 DENTAL ADHESIVE COMPOSITION 3M INNOVATIVE PROPERTIES COMPANY (US) 2023-07-26 EP claimed
US-11597789-B2 Materials for hydrophilic interaction chromatography and processes for preparation and use thereof for analysis of glycoproteins and glycopeptides WATERS TECHNOLOGIES CORPORATION (US) 2023-03-07 US claimed
US-20030116872-A1 Method for transferring from a mold a hydrophobic top coat onto an optical substrate ESSILOR INTERNATIONAL COMPAGNIE GENERALE D'OPTIQUE (FR) 2003-06-26 US claimed
US-20030065177-A1 High boiling inhibitors for distillable, polymerizable monomers CROMPTON CORPORATION, A CORPORATION OF THE STATE OF DELAWARE 2003-04-03 US claimed
WO-2003014130-A1 HIGH BOILING INHIBITORS FOR DISTILLABLE, POLYMERIZABLE MONOMERS CROMPTON CORPORATION (US) 2003-02-20 WO claimed
WO-2002096628-A2 METHOD FOR FORMING ON-SITE A COATED OPTICAL ARTICLE ESSILOR INTERNATIONAL COMPAGNIE GENERALE D'OPTIQUE (FR) 2002-12-05 WO claimed
WO-2002096627-A1 METHOD FOR TRANSFERRING FROM A MOLD A HYDROPHOBIC TOP COAT ONTO AN OPTICAL SUBSTRATE. ESSILOR INTERNATIONAL COMPAGNIE GENERALE D'OPTIQUE (FR) 2002-12-05 WO claimed
US-6475347-B1 High boiling inhibitors for distillable, polymerizable monomers CROMPTON CORPORATION 2002-11-05 US claimed
EP-0593297-B1 Resin composition for coating and paint HITACHI CHEMICAL CO LTD (JP) 1997-04-16 EP claimed
US-5539051-A ACRYLATE RESIN AND ADDITION TYPE RESIN WITH PENDANT SILICON CONTAINING GROUPS, FOR CONCRETE, MASONRY, NONSTAINING HITACHI CHEMICAL COMPANY CO., LTD. (JP) 1996-07-23 US claimed
EP-0593297-A1 Resin composition for coating and paint HITACHI CHEMICAL CO., LTD. (JP) 1994-04-20 EP claimed
US-4886852-A PREPARING NONAQUEOUS DISPERSION IN ORGANIC SOLVENT, THEN NEUTRALIZATION KANSAI PAINT COMPANY, LIMITED (JP) 1989-12-12 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030065177-A1 High boiling inhibitors for distillable, polymerizable monomers ROS1, POLR1A, ACP1 TSHR 4270/4885HPGD 3452/4885ALDH1A1 1573/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.