Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 5/20 | 0.41 |
| ▸ | BACE1 | P56817 | 5/20 | 0.41 |
| ▸ | BCHE | P06276 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL25289610 | 0.98 | MEN1 (0.56) | MEN1KMT2ARAB9AHRH3POLB | |
| SCHEMBL10073807 | 0.83 | MEN1 (0.69) | MEN1KMT2ARAB9AHRH3POLB | |
| SCHEMBL16286711 | 0.82 | EGLN2 (0.44) | MEN1KMT2ARAB9AHRH3POLB | |
| SCHEMBL16286710 | 0.82 | EGLN2 (0.44) | MEN1KMT2ARAB9AHRH3POLB | |
| SCHEMBL19650807 | 0.81 | LOXL2 (0.57) | MEN1KMT2ARAB9AHRH3POLB | |
| SCHEMBL25007080 | 0.80 | JAK1 (0.47) | MEN1KMT2ARAB9AHRH3POLB | |
| SCHEMBL4514849 | 0.79 | ALDH1A1 (0.48) | MEN1KMT2ARAB9APOLBGRIN2B | |
| SCHEMBL11784013 | 0.78 | MEN1 (0.64) | MEN1KMT2ARAB9AHRH3POLB | |
| Hydrochloric Acid SCHEMBL11781854 | 0.77 | MEN1 (0.67) | MEN1KMT2ARAB9AHRH3POLB | |
| SCHEMBL27914454 | 0.77 | MEN1 (0.49) | MEN1KMT2ARAB9AHRH3POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023118558-A1 | PROCESS OF THE PREPARATION OF HYDROXYLAMINE DERIVATIVES | INTERVET INTERNATIONAL B.V. (NL) | 2023-06-29 | — | — | WO | disclosed |
| US-9533965-B2 | 2-arylbenzofuran-7-formamide compounds, preparation method and use thereof | SHANGHAI INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF SCIENCES (CN) | 2017-01-03 | — | — | US | disclosed |
| US-9533965-B2 | 2-arylbenzofuran-7-formamide compounds, preparation method and use thereof | SHANGHAI INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF SCIENCES (CN) | 2017-01-03 | — | — | US | disclosed |
| EP-2813495-B1 | 2-ARYLBENZOFURAN-7-FORMAMIDE COMPOUNDS, PREPARATION METHOD AND USE THEREOF | SHANGHAI INST MATERIA MEDICA (CN) | 2016-09-28 | — | — | EP | disclosed |
| EP-2813495-B1 | 2-ARYLBENZOFURAN-7-FORMAMIDE COMPOUNDS, PREPARATION METHOD AND USE THEREOF | SHANGHAI INST MATERIA MEDICA (CN) | 2016-09-28 | — | — | EP | disclosed |
| CN-103242273-B | 2-arylbenzofuran-7-methanamide compound, preparation method and application thereof | SHANGHAI INST MATERIA MEDICA | 2015-06-03 | — | — | CN | disclosed |
| EP-2813495-A1 | 2-ARYLBENZOFURAN-7-FORMAMIDE COMPOUNDS, PREPARATION METHOD AND USE THEREOF | Shanghai Institute of Materia Medica, Chinese Academy of Sciences (CN) | 2014-12-17 | — | — | EP | disclosed |
| EP-2813495-A1 | 2-ARYLBENZOFURAN-7-FORMAMIDE COMPOUNDS, PREPARATION METHOD AND USE THEREOF | Shanghai Institute of Materia Medica, Chinese Academy of Sciences (CN) | 2014-12-17 | — | — | EP | disclosed |
| CN-103242273-A | 2-arylbenzofuran-7-methanamide compound, preparation method and application thereof | SHANGHAI INST MATERIA MEDICA | 2013-08-14 | — | — | CN | disclosed |