Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G2A | P14555 | 2/20 | 0.45 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.44 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.42 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.42 |
| ▸ | PLA2G5 | P39877 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.41 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.41 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.41 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.40 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.40 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | PPARA | Q07869 | 1/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | LTA4H | P09960 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1628525 | 1.00 | PLA2G2A (0.45) | PLA2G2AFFAR1PLA2G10PLA2G1BPLA2G5 | |
| SCHEMBL12222354 | 0.99 | PLA2G2A (0.46) | PLA2G2AFFAR1PLA2G10PLA2G1BPLA2G5 | |
| SCHEMBL12222339 | 0.95 | FFAR1 (0.46) | PLA2G2AFFAR1PLA2G10PLA2G1BPLA2G5 | |
| SCHEMBL1630192 | 0.89 | PLA2G2A (0.45) | PLA2G2AFFAR1PLA2G10PLA2G1BPLA2G5 | |
| SCHEMBL15868179 | 0.89 | PLA2G2A (0.45) | PLA2G2AFFAR1PLA2G10PLA2G1BPLA2G5 | |
| SCHEMBL12222356 | 0.85 | PLA2G2A (0.46) | PLA2G2AFFAR1PLA2G10PLA2G1BPLA2G5 | |
| SCHEMBL1629423 | 0.84 | PLA2G2A (0.44) | PLA2G2AFFAR1PLA2G10PLA2G1BPLA2G5 | |
| SCHEMBL1631257 | 0.83 | PLA2G2A (0.43) | PLA2G2APLA2G10PLA2G1BPLA2G5ADRB2 | |
| SCHEMBL12222345 | 0.82 | MEN1 (0.43) | PLA2G2AFFAR1PLA2G10PLA2G1BPLA2G5 | |
| SCHEMBL14865518 | 0.82 | MEN1 (0.51) | FFAR1ADRB2ADRB1ADRB3MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140194025-A1 | Production of Highly Concentrated Solutions of Self-Assembling Proteins | FREUDENBERG FORSCHUNGSDIENSTE KG (DE) | 2014-07-10 | — | — | US | disclosed |
| US-20120085262-A1 | Production of Highly Concentrated Solutions of Self-Assembling Proteins | FREUDENBERG FORSCHUNGSDIENSTE KG (DE) | 2012-04-12 | — | — | US | disclosed |