SCHEMBL1630192

SCHEMBL1630192

COC(COCC(=O)O)COC(COCC(=O)O)COC(COCC(=O)O)COC(COc1ccccc1)COC(COc1ccccc1)COC(COCCCc1ccccc1)COc1ccccc1

nearest known ligand 0.45

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
▸ PLA2G2A P14555 2/20 0.45
▸ PLA2G10 O15496 1/20 0.44
▸ PLA2G1B P04054 1/20 0.44
▸ PLA2G5 P39877 1/20 0.44
▸ FFAR1 O14842 2/20 0.44
▸ PPARG P37231 3/20 0.40
▸ PPARA Q07869 2/20 0.40
▸ S1PR1 P21453 1/20 0.40
▸ S1PR3 Q99500 1/20 0.40
▸ PPARD Q03181 1/20 0.39
▸ MEN1 O00255 1/20 0.39
▸ NPC1 O15118 1/20 0.39
▸ RAB9A P51151 1/20 0.39
▸ KMT2A Q03164 1/20 0.39
▸ FFAR4 Q5NUL3 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15868179 1.00 PLA2G2A (0.45) PLA2G2APLA2G10PLA2G1BPLA2G5FFAR1
SCHEMBL1628873 0.89 PLA2G2A (0.45) PLA2G2APLA2G10PLA2G1BPLA2G5FFAR1
SCHEMBL1628525 0.89 PLA2G2A (0.45) PLA2G2APLA2G10PLA2G1BPLA2G5FFAR1
SCHEMBL12222354 0.88 PLA2G2A (0.46) PLA2G2APLA2G10PLA2G1BPLA2G5FFAR1
SCHEMBL12222339 0.86 FFAR1 (0.46) PLA2G2APLA2G10PLA2G1BPLA2G5FFAR1
SCHEMBL12222365 0.78 PLA2G2A (0.51) PLA2G2APLA2G10PLA2G1BPLA2G5FFAR1
SCHEMBL12222356 0.78 PLA2G2A (0.46) PLA2G2APLA2G10PLA2G1BPLA2G5FFAR1
SCHEMBL12222379 0.77 PLA2G2A (0.48) PLA2G2APLA2G10PLA2G1BPLA2G5FFAR1
SCHEMBL1629423 0.77 PLA2G2A (0.44) PLA2G2APLA2G10PLA2G1BPLA2G5FFAR1
SCHEMBL12222371 0.77 LMNA (0.50) PLA2G2APLA2G10PLA2G1BPLA2G5FFAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20140194025-A1 Production of Highly Concentrated Solutions of Self-Assembling Proteins FREUDENBERG FORSCHUNGSDIENSTE KG (DE) 2014-07-10 — — US disclosed
US-20120085262-A1 Production of Highly Concentrated Solutions of Self-Assembling Proteins FREUDENBERG FORSCHUNGSDIENSTE KG (DE) 2012-04-12 — — US disclosed
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