SCHEMBL16289451

SCHEMBL16289451

O=C=NCCCC1CCCCC1CCCN=C=O

nearest known ligand 0.33

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.33
KEAP1 Q14145 1/20 0.30
NFE2L2 Q16236 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29853848 0.94 KEAP1 (0.33) ALDH1A1KEAP1NFE2L2
SCHEMBL29023921 0.92 KEAP1 (0.30) KEAP1NFE2L2
SCHEMBL16289800 0.86 ALDH1A1 (0.36) ALDH1A1
SCHEMBL34699 0.85 ALDH1A1 (0.35) ALDH1A1
SCHEMBL45977 0.84
SCHEMBL3462014 0.81 CYP1A2 (0.45) ALDH1A1KEAP1NFE2L2
SCHEMBL20798645 0.81 CYP1A2 (0.45) ALDH1A1KEAP1NFE2L2
SCHEMBL19853228 0.81 CYP1A2 (0.45) ALDH1A1KEAP1NFE2L2
SCHEMBL19969578 0.81 CYP1A2 (0.45) ALDH1A1KEAP1NFE2L2
SCHEMBL19849589 0.81 CYP1A2 (0.45) ALDH1A1KEAP1NFE2L2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2601317-B1 COMPOSITIONS COMPRISING AT LEAST ONE COMPOUND CONTAINING A CARBAMOYL SULFONATE GROUP AND USE OF THE SAME AS TANNING AGENTS LANXESS DEUTSCHLAND GMBH (DE) 2014-12-17 EP claimed