Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | HPGD | P15428 | 4/20 | 0.43 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.40 |
| ▸ | NPC1 | O15118 | 4/20 | 0.40 |
| ▸ | RAB9A | P51151 | 4/20 | 0.40 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7994480 | 1.00 | ALDH1A1 (0.43) | ALDH1A1HPGDTAAR1SMN1; SMN2NPC1 | |
| SCHEMBL2127670 | 0.98 | ALDH1A1 (0.44) | ALDH1A1HPGDTAAR1SMN1; SMN2NPC1 | |
| SCHEMBL4290928 | 0.82 | ALDH1A1 (0.46) | ALDH1A1HPGDTAAR1SMN1; SMN2NPC1 | |
| SCHEMBL10569720 | 0.82 | ALDH1A1 (0.46) | ALDH1A1HPGDTAAR1SMN1; SMN2NPC1 | |
| SCHEMBL10568015 | 0.82 | ALDH1A1 (0.46) | ALDH1A1HPGDTAAR1SMN1; SMN2NPC1 | |
| SCHEMBL10568010 | 0.82 | ALDH1A1 (0.46) | ALDH1A1HPGDTAAR1SMN1; SMN2NPC1 | |
| SCHEMBL11626141 | 0.82 | ALDH1A1 (0.46) | ALDH1A1HPGDTAAR1SMN1; SMN2NPC1 | |
| SCHEMBL22607754 | 0.82 | ALDH1A1 (0.46) | ALDH1A1HPGDTAAR1SMN1; SMN2NPC1 | |
| SCHEMBL22607753 | 0.82 | ALDH1A1 (0.46) | ALDH1A1HPGDTAAR1SMN1; SMN2NPC1 | |
| SCHEMBL5925034 | 0.82 | HPGD (0.47) | ALDH1A1HPGDTAAR1SMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7989544-B2 | Amphiphilic polymer capsules and related methods of interfacial assembly | UNIVERSITY OF MASSACHUSETTS (US) | 2011-08-02 | — | — | US | disclosed |
| US-20110091533-A1 | Amphiphilic polymer capsules and related methods of interfacial assembly | NATIONAL SCIENCE FOUNDATION | 2011-04-21 | — | — | US | disclosed |
| US-7851543-B2 | Amphiphilic polymer capsules and related methods of interfacial assembly | UNIVERSITY OF MASSACHUSETTS (US) | 2010-12-14 | — | — | US | disclosed |
| US-20100036061-A1 | Amphiphilic Polymer Capsules and Related Methods of Interfacial Assembly | NATIONAL SCIENCE FOUNDATION | 2010-02-11 | — | — | US | disclosed |
| US-7598313-B2 | Amphiphilic polymer capsules and related methods of interfacial assembly | UNIVERSITY OF MASSACHUSETTS (US) | 2009-10-06 | — | — | US | disclosed |
| EP-1663469-A1 | AMPHIPHILIC POLYMER CAPSULES AND RELATED METHODS OF INTERFACIAL ASSEMBLY | The University of Massachusetts (US) | 2006-06-07 | — | — | EP | disclosed |
| US-20050096454-A1 | Amphiphilic polymer capsules and related methods of interfacial assembly | UNIVERSITY OF MASSACHUSETTS | 2005-05-05 | — | — | US | disclosed |
| WO-2005025736-A1 | AMPHIPHILIC POLYMER CAPSULES AND RELATED METHODS OF INTERFACIAL ASSEMBLY | UNIVERSITY OF MASSACHUSETTS (US) | 2005-03-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110091533-A1 | Amphiphilic polymer capsules and related methods of interfacial assembly | SQLE, COASY, PHOSPHO1 | ALDH1A1 4337/4885HPGD 636/4885TAAR1 1293/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.