SCHEMBL16290355

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL29237837	0.82	CA1 (0.39)	CA1CA2CA7CA9
	SCHEMBL29237773	0.78	CA1 (0.36)	CA1CA2CA7CA9
	SCHEMBL29237776	0.78	CA1 (0.36)	CA1CA2CA7CA9
	SCHEMBL16290337	0.78	CA1 (0.41)	CA1CA2CA7CA9EPAS1
	SCHEMBL29604920	0.78	CA1 (0.41)	CA1CA2CA7CA9PARP1
	SCHEMBL29123808	0.74	CA1 (0.41)	CA1CA2CA7CA9EPAS1
	SCHEMBL16290453	0.73	EPAS1 (0.33)	EPAS1
	SCHEMBL30856849	0.73	EPAS1 (0.41)	EPAS1
	SCHEMBL25003063	0.70	CDK5 (0.44)	CA1CA2CA7CA9EPAS1
	SCHEMBL16556274	0.70	MEN1 (0.31)	EPAS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.