SCHEMBL25003063

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL29237779	0.82	CDK5 (0.42)	CDK5PIM1CSNK1A1ROCK1DYRK1A
	SCHEMBL29237856	0.78	PIM1 (0.39)	CDK5PIM1CSNK1A1ROCK1DYRK1A
	SCHEMBL29237858	0.78	PIM1 (0.39)	CDK5PIM1CSNK1A1ROCK1DYRK1A
	SCHEMBL25002993	0.78	ALDH1A1 (0.45)	CDK5PARP10PARP11CA1CA2
	SCHEMBL22989994	0.78	CDK5 (0.44)	CDK5PIM1CSNK1A1ROCK1DYRK1A
	SCHEMBL14938952	0.73	CDK5 (0.40)	CDK5PIM1CSNK1A1ROCK1DYRK1A
	SCHEMBL28502513	0.73	PARP10 (0.45)	CDK5PIM1CSNK1A1ROCK1DYRK1A
	SCHEMBL38659818	0.72	HTR2A (0.36)	CDK5PIM1CSNK1A1ROCK1DYRK1A
	SCHEMBL4317715	0.70	PARP10 (0.50)	CDK5PIM1CSNK1A1ROCK1DYRK1A
	SCHEMBL16290355	0.70	CA1 (0.41)	CDK5PIM1CSNK1A1ROCK1DYRK1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.