SCHEMBL16290337

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL29237812	0.82	CA1 (0.39)	CA1CA2CA7CA9GRIA1
	SCHEMBL14430321	0.79	CA1 (0.42)	CA1CA2CA7CA9GRIA1
	SCHEMBL29237694	0.78	CA1 (0.36)	CA1CA2CA7CA9GRIA1
	SCHEMBL29237696	0.78	CA1 (0.36)	CA1CA2CA7CA9GRIA1
	SCHEMBL16290355	0.78	CA1 (0.41)	CA1CA2CA7CA9EPAS1
	SCHEMBL30856849	0.76	EPAS1 (0.41)	EPAS1
	SCHEMBL7190214	0.73	CA1 (0.40)	CA1CA2CA7CA9GRIA1
	SCHEMBL12086618	0.71	KDM4E (0.37)	CA1CA2CA7CA9GRIA1
	SCHEMBL14940327	0.71	CA1 (0.36)	CA1CA2CA7CA9GRIA1
	SCHEMBL25002993	0.70	ALDH1A1 (0.45)	CA1CA2CA7CA9MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.