Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM5C | P41229 | 4/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.51 |
| ▸ | KDM6B | O15054 | 2/20 | 0.51 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.51 |
| ▸ | KDM3A | Q9Y4C1 | 1/20 | 0.51 |
| ▸ | KDM2B | Q8NHM5 | 2/20 | 0.45 |
| ▸ | SMYD2 | Q9NRG4 | 2/20 | 0.43 |
| ▸ | HTR7 | P34969 | 1/20 | 0.42 |
| ▸ | KDM5B | Q9UGL1 | 5/20 | 0.42 |
| ▸ | KDM4A | O75164 | 2/20 | 0.42 |
| ▸ | KDM5A | P29375 | 2/20 | 0.42 |
| ▸ | EHMT2 | Q96KQ7 | 4/20 | 0.42 |
| ▸ | EHMT1 | Q9H9B1 | 4/20 | 0.42 |
| ▸ | JMJD6 | Q6NYC1 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15636986 | 0.96 | SMYD2 (0.46) | KDM5CKDM4EKDM4CKDM6BKDM2A | |
| SCHEMBL15637693 | 0.92 | KDM2B (0.51) | KDM5CKDM4CKDM6BKDM2BSMYD2 | |
| SCHEMBL15636566 | 0.90 | KDM2B (0.49) | KDM5CKDM4CKDM6BKDM2BSMYD2 | |
| SCHEMBL18708137 | 0.83 | HRH3 (0.42) | SMYD2EHMT2EHMT1HRH3MAPT | |
| SCHEMBL9736097 | 0.77 | KDM4C (0.54) | KDM5CKDM4EKDM4CKDM6BKDM2A | |
| SCHEMBL16291580 | 0.77 | CCR3 (0.55) | — | |
| SCHEMBL22005801 | 0.76 | KDM5C (0.55) | KDM5CKDM4EKDM4CKDM6BKDM2A | |
| SCHEMBL23120480 | 0.76 | KDM5C (0.50) | KDM5CKDM4EKDM4CKDM6BKDM2A | |
| SCHEMBL29607375 | 0.76 | KDM5C (0.50) | KDM5CKDM4EKDM4CKDM6BKDM2A | |
| SCHEMBL15994294 | 0.74 | CYP3A4 (0.43) | SMYD2HTR7HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140371195-A1 | INHIBITORS OF HISTONE DEMETHYLASES | GILEAD SCIENCES, INC. | 2014-12-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140371195-A1 | INHIBITORS OF HISTONE DEMETHYLASES | EHMT1, KDM1B, EHMT2 | KDM5C 31/4885KDM4E 16/4885KDM4C 56/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.