Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC2A1 | P11166 | 3/20 | 0.48 |
| ▸ | NCEH1 | Q6PIU2 | 1/20 | 0.46 |
| ▸ | TYR | P14679 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | CASP1 | P29466 | 1/20 | 0.43 |
| ▸ | CASP7 | P55210 | 1/20 | 0.43 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sulfuric Acid SCHEMBL11333298 | 1.00 | SLC2A1 (0.48) | SLC2A1NCEH1TYRKDM4EALDH1A1 | |
| Sulfuric Acid SCHEMBL416631 | 1.00 | SLC2A1 (0.48) | SLC2A1NCEH1TYRKDM4EALDH1A1 | |
| Sulfuric Acid SCHEMBL10939908 | 0.99 | SLC2A1 (0.47) | SLC2A1NCEH1TYRKDM4EALDH1A1 | |
| Sulfamate SCHEMBL9632587 | 0.96 | SLC2A1 (0.47) | SLC2A1NCEH1TYRKDM4EALDH1A1 | |
| Sulfuric Acid SCHEMBL6742835 | 0.94 | NCEH1 (0.51) | SLC2A1NCEH1KDM4EALDH1A1HPGD | |
| Sulfuric Acid SCHEMBL6136219 | 0.93 | NCEH1 (0.50) | SLC2A1NCEH1KDM4EALDH1A1HPGD | |
| SCHEMBL11381159 | 0.91 | TYR (0.47) | NCEH1TYRKDM4EALDH1A1HPGD | |
| SCHEMBL284699 | 0.91 | TYR (0.47) | NCEH1TYRKDM4EALDH1A1HPGD | |
| SCHEMBL236078 | 0.91 | TYR (0.47) | NCEH1TYRKDM4EALDH1A1HPGD | |
| SCHEMBL284188 | 0.91 | TYR (0.47) | NCEH1TYRKDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090289215-A1 | ANTIFREEZE COOLANT COMPOSITION HAVING HIGH HEAT-OXIDATION RESISTANCE | HYUNDAI MOTOR COMPANY (KR) | 2009-11-26 | — | — | US | claimed |
| CN-1718611-A | Preparation method of conductive polyaniline | SHANGHAI COLLEGE OF APPLIED TE (CN) | 2006-01-11 | — | — | CN | claimed |
| CN-1583830-A | Method for direct preparation of polyaniline solution from aniline monomer | XIBEI NUCLEAR TECHNOLOGY INST (CN) | 2005-02-23 | — | — | CN | claimed |
| CN-102977689-B | Anti-rust pigment | QINGDAO WENCHUANG TECH CO LTD | 2014-07-30 | — | — | CN | disclosed |
| CN-102226045-B | Aluminum-tripolyphosphate-doped polyaniline antirust pigment and preparation method thereof | GUIYANG FINEW CHEMICAL CO LTD | 2014-05-07 | — | — | CN | disclosed |
| CN-102977689-A | Anti-rust pigment | QINGDAO ADVANCED MARINE MATERIAL TECHNOLOGY CO LTD | 2013-03-20 | — | — | CN | disclosed |
| CN-102226045-A | Aluminum-tripolyphosphate-doped polyaniline antirust pigment and preparation method thereof | GUIYANG SHENDI CHEMICAL CO LTD | 2011-10-26 | — | — | CN | disclosed |
| US-7927566-B2 | Extraction of radionuclides by crown ether-containing extractants | Designing-Contructing and Industrial-Inculcating Enterprise “Daymos Ltd.” (RU) | 2011-04-19 | — | — | US | disclosed |
| CN-101538365-B | Method for preparing organic/inorganic acid composite doped conductive polyaniline | UNIV KUNMING SCIENCE & TECHNOLOGY | 2011-03-30 | — | — | CN | disclosed |
| US-20090289215-A1 | ANTIFREEZE COOLANT COMPOSITION HAVING HIGH HEAT-OXIDATION RESISTANCE | HYUNDAI MOTOR COMPANY (KR) | 2009-11-26 | — | — | US | disclosed |
| US-20090289215-A1 | ANTIFREEZE COOLANT COMPOSITION HAVING HIGH HEAT-OXIDATION RESISTANCE | HYUNDAI MOTOR COMPANY (KR) | 2009-11-26 | — | — | US | disclosed |
| CN-100487023-C | Preparation method of composite acids doped with conductive polyaniline | UNIV CHONGQING (CN) | 2009-05-13 | — | — | CN | disclosed |
| US-20080014133-A1 | Extraction Of Radionuclides By Crown Ether-Containing Extractants | DESIGN-CONSTRUCTION AND INDUSTRIAL-INNOVATION ENTERPRISE, LTD. "DAYMOS" (RU) | 2008-01-17 | — | — | US | disclosed |
| CN-1276940-C | Method for direct preparation of polyaniline solution from aniline monomer | NORTHWEST INST NUCLEAR TECH (CN) | 2006-09-27 | — | — | CN | disclosed |
| CN-1733820-A | Preparation method of composite acids doped with conductive polyaniline | UNIV CHONGQING (CN) | 2006-02-15 | — | — | CN | disclosed |
| CN-1718611-A | Preparation method of conductive polyaniline | SHANGHAI COLLEGE OF APPLIED TE (CN) | 2006-01-11 | — | — | CN | disclosed |
| CN-1583830-A | Method for direct preparation of polyaniline solution from aniline monomer | XIBEI NUCLEAR TECHNOLOGY INST (CN) | 2005-02-23 | — | — | CN | disclosed |
| EP-0914662-A1 | METHOD OF INCREASING POLYANILINE CONDUCTIVITY | Zipperling Kessler & Co (GmbH & Co) (DE) | 1999-05-12 | — | — | EP | disclosed |
| US-5780572-A | POLAR SOLVENT EXTRACTION OF EXCESS NONCONDUCTIVE ACID FROM POLYANILINE-ACID SALT MATERIAL | MONSANTO COMPANY (US) | 1998-07-14 | — | — | US | disclosed |
| WO-1998005042-A1 | METHOD OF INCREASING POLYANILINE CONDUCTIVITY | ZIPPERLING KESSLER & CO. (GMBH & CO.) (DE) | 1998-02-05 | — | — | WO | disclosed |