Sulfuric Acid

Sulfuric Acid

SCHEMBL6136219

CCCCc1ccc2ccccc2c1CCCC.O=S(=O)(O)O.[NaH]

nearest known ligand 0.50

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Known targets — ChEMBL curated mechanism

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

The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
NCEH1 Q6PIU2 2/20 0.50
SLC2A1 P11166 5/20 0.46
GAA P10253 1/20 0.43
TDP1 Q9NUW8 1/20 0.43
L3MBTL1 Q9Y468 1/20 0.43
HSD17B10 Q99714 2/20 0.40
CYP1A2 P05177 1/20 0.40
CYP2C9 P11712 1/20 0.40
CYP2C19 P33261 1/20 0.40
KDM4E B2RXH2 1/20 0.40
ALDH1A1 P00352 1/20 0.40
HPGD P15428 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Sulfuric Acid SCHEMBL6742835 0.98 NCEH1 (0.51) NCEH1SLC2A1GAATDP1L3MBTL1
Sulfuric Acid SCHEMBL10939908 0.94 SLC2A1 (0.47) NCEH1SLC2A1GAATDP1HSD17B10
Sulfuric Acid SCHEMBL1629207 0.93 SLC2A1 (0.48) NCEH1SLC2A1GAATDP1HSD17B10
Sulfuric Acid SCHEMBL416631 0.93 SLC2A1 (0.48) NCEH1SLC2A1GAATDP1HSD17B10
Sulfuric Acid SCHEMBL11333298 0.93 SLC2A1 (0.48) NCEH1SLC2A1GAATDP1HSD17B10
SCHEMBL2813501 0.91 NCEH1 (0.50) NCEH1GAATDP1L3MBTL1HSD17B10
SCHEMBL29832803 0.89 NCEH1 (0.51) NCEH1GAATDP1L3MBTL1HSD17B10
SCHEMBL761100 0.89 NCEH1 (0.51) NCEH1GAATDP1L3MBTL1HSD17B10
Sulfamate SCHEMBL9632587 0.89 SLC2A1 (0.47) NCEH1SLC2A1GAATDP1HSD17B10
Sulfuric Acid SCHEMBL6136221 0.88 NCEH1 (0.47) NCEH1SLC2A1GAATDP1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0969139-B1 Manufacturing process for leather-like sheet KURARAY CO (JP) 2005-05-18 EP disclosed
US-6322851-B1 PRETREATING A FIBROUS SUBSTRATE WITH AN AGENT THAT INHIBITS ADHESION; IMPREGNATING WITH A HEAT-GELLABLE POLYURETHANE EMULSION; FOLLOWED BY COAGULATING THE POLYURETHANE EMULSION; SPECIFIC MODULUS OF ELASTICITY KURARAY CO., LTD. (JP) 2001-11-27 US disclosed
EP-0969139-A2 Manufacturing process for leather-like sheet KURARAY CO., LTD. (JP) 2000-01-05 EP disclosed
US-4417918-A Herbicidal α-[3-(2-halo-4-trifluoromethylphenoxy)-6-halophenoxy]propionic acid thio esters and acids CIBA-GEIGY CORPORATION (US) 1983-11-29 US disclosed
US-4394327-A THIOESTERS CIBA-GEIGY CORPORATION (US) 1983-07-19 US disclosed
US-4353736-A CROPS OF BARLEY, WHEAT, CORN, RICE OR COATS CIBA-GEIGY CORPORATION (US) 1982-10-12 US disclosed
US-4349377-A Phenoxyphenylthioalkanecarboxylic acid amides and their use as herbicides and plant growth regulants CIBA-GEIGY CORPORATION (US) 1982-09-14 US disclosed
US-4205978-A Novel herbicidally active, nuclear-substituted phenoxy-phenoxyalkanecarboxylic acid derivatives and use thereof for controlling grass-like weeds ISHIHARA SANGYO KAISHA, LTD. (JP) 1980-06-03 US disclosed
US-4193790-A Novel herbicidally active, nuclear-substituted phenoxy-phenoxy-alkanecarboxylic acid derivatives and use thereof for controlling grass-like weeds Ishihara Sangyo Kabushiki Kaisha Ltd. (JP) 1980-03-18 US disclosed
US-4183743-A IN CROPS OF PLANTS SUCH AS CEREALS ISHIHARA SANGYO KAISHA LTD. (JP) 1980-01-15 US disclosed
US-4129573-A MAINTAINING TURF IN PBULIC AND TRAFFIC AREAS CIBA-GEIGY CORPORATION (US) 1978-12-12 US disclosed
US-4106925-A PREEMERGENT AND POSTEMERGENT ISHIHARA SANGYO KAISHA LTD. (JP) 1978-08-15 US disclosed
US-4092146-A POSTEMERGENCE HERBICIDES, PLANT GROWTH INHIBITORS, DESSICANTS, ETHERS OF CYCLOBUTENEDIONE CIBA-GEIGY CORPORATION (US) 1978-05-30 US disclosed
US-4053497-A B-HALOGENOETHYL SILANE CIBA-GEIGY CORPORATION (US) 1977-10-11 US disclosed
US-4014677-A HERBICIDES CIBA-GEIGY CORPORATION (US) 1977-03-29 US disclosed
US-3992533-A PESTICIDES, ACARICIDES CIBA-GEIGY CORPORATION (US) 1976-11-16 US disclosed
US-3973010-A Insecticidal and acaricidal composition and method with triazolyl phosphoric esters acid CIBA-GEIGY CORPORATION (US) 1976-08-03 US disclosed
US-3956306-A PESTICIDES CIBA-GEIGY CORPORATION (US) 1976-05-11 US disclosed