Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.59 |
| ▸ | HTT | P42858 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14965176 | 0.91 | POLB (0.60) | POLBHTTKMT2A | |
| SCHEMBL14965072 | 0.82 | POLB (0.62) | POLBHTTKMT2A | |
| SCHEMBL14964774 | 0.82 | POLB (0.66) | POLBHTTKMT2A | |
| SCHEMBL16293323 | 0.81 | POLB (0.61) | POLBHTTKMT2A | |
| SCHEMBL14964827 | 0.81 | POLB (0.53) | POLBHTTKMT2A | |
| SCHEMBL17599008 | 0.81 | KMT2A (0.77) | POLBHTTKMT2A | |
| SCHEMBL14965055 | 0.79 | POLB (0.65) | POLBHTTKMT2A | |
| SCHEMBL14965006 | 0.79 | POLB (0.66) | POLBHTTKMT2A | |
| SCHEMBL17599009 | 0.78 | ADRB3 (0.58) | — | |
| SCHEMBL14964970 | 0.78 | POLB (0.59) | POLBHTTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140371203-A1 | Thieno- and furo - pyrimidines and pyridines, useful as potassium channel inhibitors | XENTION LIMITED (GB) | 2014-12-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140371203-A1 | Thieno- and furo - pyrimidines and pyridines, useful as potassium channel inhibitors | KCNA3, KCNJ1, KCNJ11 | POLB 3507/4885HTT 2759/4885KMT2A 1039/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.