Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.77 |
| ▸ | POLB | P06746 | 1/20 | 0.77 |
| ▸ | HTT | P42858 | 1/20 | 0.77 |
| ▸ | LMNA | P02545 | 1/20 | 0.69 |
| ▸ | MEN1 | O00255 | 1/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14964774 | 0.90 | POLB (0.66) | KMT2APOLBHTTLMNA | |
| SCHEMBL14965036 | 0.90 | LMNA (0.67) | KMT2APOLBHTTLMNA | |
| SCHEMBL16292937 | 0.88 | POLB (0.80) | KMT2APOLBHTT | |
| SCHEMBL16294397 | 0.88 | LMNA (0.72) | KMT2APOLBHTTLMNAMEN1 | |
| SCHEMBL14965005 | 0.87 | LMNA (0.64) | KMT2APOLBHTTLMNA | |
| SCHEMBL14965055 | 0.87 | POLB (0.65) | KMT2APOLBHTTLMNA | |
| SCHEMBL16293296 | 0.86 | POLB (0.62) | KMT2APOLBHTT | |
| SCHEMBL16293434 | 0.86 | ADRB2 (0.64) | LMNA | |
| SCHEMBL4552668 | 0.86 | LMNA (0.72) | KMT2APOLBHTTLMNAMEN1 | |
| SCHEMBL4432115 | 0.86 | LMNA (0.72) | KMT2APOLBHTTLMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9290511-B2 | Thieno-pyrimidines, useful as potassium channel inhibitors | XENTION LIMITED (GB) | 2016-03-22 | — | — | US | disclosed |
| CN-104011054-A | Thieno- and furo-pyrimidines and pyridines, useful as potassium channel inhibitors | XENTION LTD | 2014-08-27 | — | — | CN | disclosed |