Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 3/20 | 0.53 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.44 |
| ▸ | NOS2 | P35228 | 1/20 | 0.42 |
| ▸ | CES2 | O00748 | 1/20 | 0.39 |
| ▸ | CES1 | P23141 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.38 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | SRC | P12931 | 1/20 | 0.38 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1629331 | 1.00 | TRPA1 (0.53) | TRPA1ALOX5NOS2CES2CES1 | |
| SCHEMBL8893738 | 1.00 | TRPA1 (0.53) | TRPA1ALOX5NOS2CES2CES1 | |
| SCHEMBL1629334 | 1.00 | TRPA1 (0.53) | TRPA1ALOX5NOS2CES2CES1 | |
| SCHEMBL349596 | 0.85 | TRPA1 (0.56) | TRPA1ALOX5CES2CES1HPGD | |
| SCHEMBL1336581 | 0.85 | TRPA1 (0.56) | TRPA1ALOX5CES2CES1HPGD | |
| SCHEMBL3647763 | 0.81 | HPGD (0.42) | ALOX5NOS2CES2CES1LMNA | |
| SCHEMBL553683 | 0.80 | ALOX5 (0.40) | TRPA1ALOX5NOS2CES2CES1 | |
| SCHEMBL3191062 | 0.79 | TRPA1 (0.50) | TRPA1LMNAHPGDCYP2D6HCAR2 | |
| SCHEMBL9222442 | 0.76 | TRPA1 (0.64) | TRPA1NOS2LMNAADRA2AADRA2C | |
| SCHEMBL28363855 | 0.75 | TRPA1 (0.50) | TRPA1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9039870-B2 | Method for producing alkaline (meth)acrylamides | CLARIANT FINANCE (BVI) LIMITED (VG) | 2015-05-26 | — | — | US | disclosed |
| US-20110089020-A1 | Continuous Method for Producing Amides of Ethylenically Unsaturated Carboxylic Acids | CLARIANT FINANCE (BVI) LIMITED (VG) | 2011-04-21 | — | — | US | disclosed |
| US-20100032284-A1 | Method For Producing Alkaline (Meth)Acrylamides | CLARIANT INTERNATIONAL LTD. (CH) | 2010-02-11 | — | — | US | disclosed |