SCHEMBL1629356

SCHEMBL1629356

C=CC(=O)OCCc1ccc(-c2ccc(N(c3ccc(C)c(C)c3)c3ccc(C)c(C)c3)cc2)cc1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
THRB P10828 5/20 0.40
TSHR P16473 3/20 0.36
HPGD P15428 1/20 0.36
ALDH1A1 P00352 2/20 0.36
TP53 P04637 2/20 0.36
HIF1A Q16665 2/20 0.36
HSD17B10 Q99714 1/20 0.36
MET P08581 5/20 0.35
CA12 O43570 2/20 0.35
CA4 P22748 2/20 0.35
CA6 P23280 2/20 0.35
CA5A P35218 2/20 0.35
CA7 P43166 2/20 0.35
CA9 Q16790 2/20 0.35
CA14 Q9ULX7 2/20 0.35
CA5B Q9Y2D0 2/20 0.35
CA1 P00915 1/20 0.35
HCAR2 Q8TDS4 1/20 0.35
AKR1B10 O60218 2/20 0.34
AKR1B1 P15121 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12144663 0.97 THRB (0.38) THRBTSHRHPGDALDH1A1TP53
SCHEMBL1629357 0.96 THRB (0.43) THRBTSHRHPGDALDH1A1TP53
SCHEMBL2609790 0.96 THRB (0.43) THRBTSHRHPGDALDH1A1TP53
SCHEMBL25830853 0.96 THRB (0.42) THRBTSHRHPGDALDH1A1TP53
SCHEMBL13777501 0.94 THRB (0.41) THRBTSHRHPGDALDH1A1
SCHEMBL14195367 0.93 THRB (0.36) THRBTSHRHPGDALDH1A1TP53
SCHEMBL25445750 0.93 THRB (0.49) THRBTSHRHPGDALDH1A1TP53
SCHEMBL21695713 0.93 THRB (0.40) THRBTSHRHPGDALDH1A1TP53
SCHEMBL19229847 0.92 THRB (0.36) THRBTSHRHPGDALDH1A1TP53
SCHEMBL12680101 0.91 TSHR (0.45) THRBTSHRHPGDALDH1A1TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 52 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11754901-B2 Electrochromic device, wearable device, and method for driving electrochromic device RICOH COMPANY, LTD. (JP) 2023-09-12 US disclosed
US-11415904-B2 Image forming method and image forming system Konica Minolta, Inc. (JP) 2022-08-16 US disclosed
US-20210318632-A1 IMAGE FORMING METHOD AND IMAGE FORMING SYSTEM Konica Minolta, Inc. (JP) 2021-10-14 US disclosed
US-20190285997-A1 IMAGE FORMING APPARATUS RICOH COMPANY, LTD. (JP) 2019-09-19 US disclosed
US-20170329199-A1 ELECTROCHROMIC DEVICE RICOH COMPANY, LTD. (JP) 2017-11-16 US disclosed
US-20170329198-A1 ELECTROCHROMIC ELEMENT RICOH COMPANY, LTD. (JP) 2017-11-16 US disclosed
US-20170235203-A1 ELECTROCHROMIC ELEMENT AND ELECTROCHROMIC DIMMING ELEMENT RICOH COMPANY, LTD. (JP) 2017-08-17 US disclosed
US-9046863-B2 Image forming apparatus, and image forming method RICOH COMPANY, LTD. (JP) 2015-06-02 US disclosed
US-9046863-B2 Image forming apparatus, and image forming method RICOH COMPANY, LTD. (JP) 2015-06-02 US disclosed
US-8835084-B2 Electrophotographic photoreceptor, and image forming method, image forming apparatus and process cartridge using same RICOH COMPANY, LTD. (JP) 2014-09-16 US disclosed
US-20110020740-A1 IMAGE FORMING APPARATUS RICOH COMPANY, LTD (JP) 2011-01-27 US disclosed
US-20100330475-A1 IMAGE FORMING APPARATUS, PROCESS CARTRIDGE, AND IMAGE BEARING MEMBER RICOH COMPANY LIMITED (JP) 2010-12-30 US disclosed
US-20100316423-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, METHOD OF MANUFACTURING ELECTROPHOTOGRAPHIC PHOTORECEPTOR, PROCESS CARTRIDGE, AND IMAGE FORMING APPARATUS RICOH COMPANY, LTD. (JP) 2010-12-16 US disclosed
US-20100316423-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, METHOD OF MANUFACTURING ELECTROPHOTOGRAPHIC PHOTORECEPTOR, PROCESS CARTRIDGE, AND IMAGE FORMING APPARATUS RICOH COMPANY, LTD. (JP) 2010-12-16 US disclosed
US-20100232831-A1 Electrophotographic Photorecptor, Method Of Manufacturing Electrophotographic Photorecptor, Image Forming Apparatus, And Process Cartridge RICOH COMPANY, LTD. (JP) 2010-09-16 US disclosed
US-20100232831-A1 Electrophotographic Photorecptor, Method Of Manufacturing Electrophotographic Photorecptor, Image Forming Apparatus, And Process Cartridge RICOH COMPANY, LTD. (JP) 2010-09-16 US disclosed
US-20100172670-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, IMAGE FORMING APPARATUS AND PROCESS CARTRIDGE THEREFOR USING THE ELECTROPHOTOGRAPHIC PHOTORECEPTOR RICOH COMPANY, LTD. (JP) 2010-07-08 US disclosed
US-20100172670-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, IMAGE FORMING APPARATUS AND PROCESS CARTRIDGE THEREFOR USING THE ELECTROPHOTOGRAPHIC PHOTORECEPTOR RICOH COMPANY, LTD. (JP) 2010-07-08 US disclosed
US-20090185821-A1 Electrophotographic photoreceptor, and image formihg appratus and process cartridge using same RICOH COMPANY, LTD (JP) 2009-07-23 US disclosed
US-20080304867-A1 Image bearing member, method of manufacturing the same, image formation method, image forming apparatus and process cartridge RICOH COMPANY, LTD. 2008-12-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080304867-A1 Image bearing member, method of manufacturing the same, image formation method, image forming apparatus and process cartridge KDM1A, C9, JMJD6 THRB 4693/4885TSHR 4581/4885HPGD 2767/4885
US-20170235203-A1 ELECTROCHROMIC ELEMENT AND ELECTROCHROMIC DIMMING ELEMENT TET2, TET1, TET3 THRB 658/4885TSHR 1413/4885HPGD 1942/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.