Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.51 |
| ▸ | MAPT | P10636 | 5/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | HPGD | P15428 | 3/20 | 0.51 |
| ▸ | NPC1 | O15118 | 4/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | ESR1 | P03372 | 1/20 | 0.45 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7946523 | 0.80 | MAPT (0.58) | KMT2AMAPTL3MBTL1MEN1HPGD | |
| SCHEMBL14980300 | 0.80 | KMT2A (0.51) | KMT2AMAPTL3MBTL1MEN1HPGD | |
| SCHEMBL9547929 | 0.78 | KMT2A (0.60) | KMT2AMAPTL3MBTL1MEN1HPGD | |
| SCHEMBL6831485 | 0.76 | ALDH1A1 (0.59) | KMT2AMAPTL3MBTL1LMNATDP1 | |
| SCHEMBL17698007 | 0.75 | MAPT (0.57) | KMT2AMAPTL3MBTL1MEN1HPGD | |
| SCHEMBL8608672 | 0.75 | MAPT (0.57) | KMT2AMAPTL3MBTL1MEN1HPGD | |
| SCHEMBL11100298 | 0.75 | MAPT (0.57) | KMT2AMAPTL3MBTL1MEN1HPGD | |
| SCHEMBL9547932 | 0.75 | KMT2A (0.57) | KMT2AMAPTL3MBTL1MEN1HPGD | |
| SCHEMBL2175972 | 0.75 | NPC1 (0.57) | KMT2AMAPTL3MBTL1MEN1HPGD | |
| SCHEMBL4530995 | 0.75 | ESR1 (0.50) | KMT2AMAPTL3MBTL1MEN1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8362159-B2 | Degradable biocompatible block copolymer | EIDGENOSSISCHE TECHNISCHE HOCHSCHULE ZURICH (CH) | 2013-01-29 | — | — | US | disclosed |
| US-20110093066-A1 | Degradable Biocompatible Block Copolymer | EIDGENOSSISCHE TECHNISCHE HOCHSCHULE ZURICH (CH) | 2011-04-21 | — | — | US | disclosed |
| US-20060178477-A1 | Degradable biocompatible block copolymer | EIDGENOSSISCHE TECHNISCHE HOCHSCHULE ZURICH (CH) | 2006-08-10 | — | — | US | disclosed |