Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 5/20 | 0.57 |
| ▸ | RAB9A | P51151 | 4/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.57 |
| ▸ | MAPT | P10636 | 4/20 | 0.57 |
| ▸ | MEN1 | O00255 | 4/20 | 0.57 |
| ▸ | HPGD | P15428 | 2/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | ESR1 | P03372 | 1/20 | 0.50 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.50 |
| ▸ | ELANE | P08246 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11461528 | 0.87 | HTT (0.57) | NPC1RAB9AKMT2AMAPTMEN1 | |
| SCHEMBL7611620 | 0.85 | MAPT (0.62) | NPC1RAB9AKMT2AMAPTMEN1 | |
| SCHEMBL9547929 | 0.84 | KMT2A (0.60) | NPC1RAB9AKMT2AMAPTMEN1 | |
| SCHEMBL9200565 | 0.83 | ALDH1A1 (0.60) | NPC1RAB9AKMT2AMAPTL3MBTL1 | |
| SCHEMBL7946523 | 0.82 | MAPT (0.58) | NPC1RAB9AKMT2AMAPTMEN1 | |
| SCHEMBL12231836 | 0.82 | USP2 (0.55) | NPC1RAB9AKMT2AMAPTMEN1 | |
| SCHEMBL20055247 | 0.81 | HPGD (0.58) | NPC1RAB9AKMT2AMAPTMEN1 | |
| SCHEMBL31468786 | 0.81 | NPC1 (0.54) | NPC1RAB9AKMT2AMAPTMEN1 | |
| SCHEMBL28689137 | 0.81 | L3MBTL1 (0.50) | NPC1KMT2AMAPTMEN1HPGD | |
| SCHEMBL13275229 | 0.81 | LMNA (0.53) | NPC1RAB9AKMT2AHPGDL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107876092-B | Application of titanium catalyst with cyclic structure as reaction catalyst for synthesizing benzyl carbonate or diphenyl carbonate by ester exchange | 华东理工大学 | 2023-01-10 | — | — | CN | claimed |
| US-20200163916-A1 | PROBENECID FOR USE IN TREATING EPILEPTIC DISEASES, DISORDERS OR CONDITIONS | PARIS SCIENCES ET LETTRES - QUARTIER LATIN (FR) | 2020-05-28 | — | — | US | disclosed |
| CN-108633282-A | Method for preparing crosslinked pressure sensitive adhesives using light emitting diode crosslinking | 3M创新有限公司 | 2018-10-09 | — | — | CN | disclosed |
| US-9328335-B2 | Method to produce acetyldiacylglycerols (ac-TAGs) by expression of an acetyltransferase gene isolated from Euonymus alatus (burning bush) | BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY (US) | 2016-05-03 | — | — | US | disclosed |
| US-20130116462-A1 | METHOD TO PRODUCE ACETYLDIACYLGLYCEROLS (AC-TAGS) BY EXPRESSION OF AN ACETYLTRANSFERASE GENE ISOLATED FROM EUONYMUS ALATUS (BURNING BUSH) | BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY (US) | 2013-05-09 | — | — | US | disclosed |
| WO-2011082253-A2 | A METHOD TO PRODUCE ACETYLDIACYLGLYCEROLS (AC-TAGS) BY EXPRESSION OFAN ACETYLTRANSFERASE GENE ISOLATED FROM EUONYMUS ALATUS (BURNING BUSH) | BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY (US) | 2011-07-07 | — | — | WO | disclosed |
| US-7429473-B2 | Diacylglycerol acyltransferase genes, proteins, and uses thereof | MICHIGAN STATE UNIVERSITY (US) | 2008-09-30 | — | — | US | disclosed |
| CN-100404636-C | Single-layer coated adhesive tape | 3M INNOVATIVE PROPERTIES CO (US) | 2008-07-23 | — | — | CN | disclosed |
| US-20070028329-A1 | Diacylglycerol acyltransferase genes, proteins, and uses thereof | BOARD OF TRUSTEES OPERATING MICHIGAN STATE UNIVERSITY | 2007-02-01 | — | — | US | disclosed |
| CN-1882668-A | Single-layer coated adhesive tape | 3M INNOVATIVE PROPERTIES CO (US) | 2006-12-20 | — | — | CN | disclosed |
| US-7122367-B2 | Diacylglycerol acyltransferase genes, proteins, and uses thereof | BOARD OF TRUSTEES OPERATING MICHIGAN STATE UNIVERSITY (US) | 2006-10-17 | — | — | US | disclosed |
| US-20050130284-A1 | Diacylglycerol acyltransferase genes, proteins, and uses thereof | BOARD OF TRUSTEES OPERATING MICHIGAN STATE UNIVERSITY, THE | 2005-06-16 | — | — | US | disclosed |
| EP-1484392-A1 | Diacylglycerol acyltransferase genes, proteins and uses thereof | Board of Trustees Operating Michigan State University (US) | 2004-12-08 | — | — | EP | disclosed |
| US-4054719-A | ACRYLIC ESTER, TERTIARY AMINE | AMERICAN CYANAMID COMPANY (US) | 1977-10-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200163916-A1 | PROBENECID FOR USE IN TREATING EPILEPTIC DISEASES, DISORDERS OR CONDITIONS | NLN, CLN6, SLC1A2 | NPC1 216/4885RAB9A 1266/4885KMT2A 2257/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.