Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.51 |
| ▸ | CHUK | O15111 | 1/20 | 0.44 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.43 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.43 |
| ▸ | MAPK14 | Q16539 | 3/20 | 0.43 |
| ▸ | MAPK13 | O15264 | 2/20 | 0.43 |
| ▸ | MAPK12 | P53778 | 2/20 | 0.43 |
| ▸ | MAPK11 | Q15759 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | TLR3 | O15455 | 1/20 | 0.40 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | KIT | P10721 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16295995 | 0.90 | CHUK (0.50) | ACHECHUKMAPK14MAPK13MAPK12 | |
| SCHEMBL16294627 | 0.82 | MAPK14 (0.45) | ACHEPDE3BPDE3AMAPK14MAPT | |
| SCHEMBL16294674 | 0.82 | ACHE (0.47) | ACHECHUKMAPK14MAPTKDM4E | |
| SCHEMBL4135200 | 0.81 | ACHE (0.56) | ACHECHUKPDE3BPDE3AMAPK14 | |
| SCHEMBL5159528 | 0.76 | KDM4E (0.56) | PDE3BPDE3AMAPTKDM4EALDH1A1 | |
| SCHEMBL16305433 | 0.73 | PREP (0.38) | CHUKMAPK14MAPK13MAPK12MAPK11 | |
| SCHEMBL16294882 | 0.71 | MAP2 (0.58) | CHUKKDM4EALDH1A1HPGDRAB9A | |
| SCHEMBL30667681 | 0.70 | ACHE (0.79) | ACHECHUKMAPK14MAPK13MAPK12 | |
| SCHEMBL27098859 | 0.70 | ACHE (0.79) | ACHECHUKMAPK14MAPK13MAPK12 | |
| SCHEMBL4140165 | 0.68 | PTGS1 (0.56) | ACHECHUKMAPTKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014198844-A1 | PROTEIN KINASE INHIBITORS | LYTIX BIOPHARMA AS (NO) | 2014-12-18 | — | — | WO | disclosed |
| WO-2014198848-A2 | COMPOUNDS | LYTIX BIOPHARMA AS (NO) | 2014-12-18 | — | — | WO | disclosed |