Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 11/20 | 0.48 |
| ▸ | ITGA2B | P08514 | 11/20 | 0.48 |
| ▸ | ITGAV | P06756 | 1/20 | 0.47 |
| ▸ | S1PR5 | Q9H228 | 4/20 | 0.46 |
| ▸ | P2RX7 | Q99572 | 3/20 | 0.45 |
| ▸ | HRH2 | P25021 | 1/20 | 0.44 |
| ▸ | HRH1 | P35367 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16343396 | 1.00 | ITGB3 (0.48) | ITGB3ITGA2BITGAVS1PR5P2RX7 | |
| SCHEMBL16295969 | 1.00 | ITGB3 (0.48) | ITGB3ITGA2BITGAVS1PR5P2RX7 | |
| SCHEMBL22384305 | 0.94 | ITGB3 (0.47) | ITGB3ITGA2BITGAVP2RX7HRH2 | |
| SCHEMBL16305642 | 0.94 | ITGB3 (0.47) | ITGB3ITGA2BITGAVP2RX7HRH2 | |
| SCHEMBL16343092 | 0.94 | ITGB3 (0.50) | ITGB3ITGA2BITGAVS1PR5P2RX7 | |
| SCHEMBL16295738 | 0.94 | ITGB3 (0.50) | ITGB3ITGA2BITGAVS1PR5P2RX7 | |
| SCHEMBL16295824 | 0.90 | ITGB3 (0.49) | ITGB3ITGA2BITGAVP2RX7HRH2 | |
| SCHEMBL16295823 | 0.90 | ITGB3 (0.49) | ITGB3ITGA2BITGAVP2RX7HRH2 | |
| SCHEMBL22756121 | 0.89 | ITGB3 (0.55) | ITGB3ITGA2BITGAVP2RX7 | |
| SCHEMBL17834832 | 0.89 | S1PR5 (0.49) | ITGB3ITGA2BS1PR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3008056-A1 | NOVEL GLP-1 RECEPTOR MODULATORS | Receptos, Inc. (US) | 2016-04-20 | — | — | EP | disclosed |
| WO-2014201172-A1 | NOVEL GLP-1 RECEPTOR MODULATORS | RECEPTOS, INC. (US) | 2014-12-18 | — | — | WO | disclosed |