Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 12/20 | 0.47 |
| ▸ | ITGA2B | P08514 | 12/20 | 0.47 |
| ▸ | ITGAV | P06756 | 1/20 | 0.46 |
| ▸ | HRH2 | P25021 | 1/20 | 0.43 |
| ▸ | HRH1 | P35367 | 1/20 | 0.43 |
| ▸ | P2RX7 | Q99572 | 3/20 | 0.43 |
| ▸ | LTA4H | P09960 | 1/20 | 0.42 |
| ▸ | YAP1 | P46937 | 1/20 | 0.41 |
| ▸ | BCHE | P06276 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16305642 | 1.00 | ITGB3 (0.47) | ITGB3ITGA2BITGAVHRH2HRH1 | |
| SCHEMBL16295540 | 0.94 | ITGB3 (0.48) | ITGB3ITGA2BITGAVHRH2HRH1 | |
| SCHEMBL16343396 | 0.94 | ITGB3 (0.48) | ITGB3ITGA2BITGAVHRH2HRH1 | |
| SCHEMBL16295969 | 0.94 | ITGB3 (0.48) | ITGB3ITGA2BITGAVHRH2HRH1 | |
| SCHEMBL16295824 | 0.94 | ITGB3 (0.49) | ITGB3ITGA2BITGAVHRH2HRH1 | |
| SCHEMBL16295823 | 0.94 | ITGB3 (0.49) | ITGB3ITGA2BITGAVHRH2HRH1 | |
| SCHEMBL16343092 | 0.90 | ITGB3 (0.50) | ITGB3ITGA2BITGAVHRH2HRH1 | |
| SCHEMBL16295738 | 0.90 | ITGB3 (0.50) | ITGB3ITGA2BITGAVHRH2HRH1 | |
| SCHEMBL22756121 | 0.88 | ITGB3 (0.55) | ITGB3ITGA2BITGAVP2RX7 | |
| SCHEMBL16305994 | 0.88 | HRH2 (0.48) | ITGB3ITGA2BITGAVHRH2HRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3230276-B1 | GLP-1 RECEPTOR MODULATORS | CELGENE INT II SARL (CH) | 2020-09-02 | — | — | EP | disclosed |