⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8866037 | 0.81 | TRPA1 (0.48) | — | |
| SCHEMBL142183 | 0.79 | — | — | |
| SCHEMBL5945922 | 0.77 | — | — | |
| SCHEMBL826974 | 0.77 | — | — | |
| SCHEMBL7912 | 0.77 | — | — | |
| SCHEMBL277930 | 0.77 | — | — | |
| SCHEMBL19159706 | 0.77 | — | — | |
| SCHEMBL11550514 | 0.77 | — | — | |
| SCHEMBL2000883 | 0.77 | — | — | |
| Hydrochloric Acid SCHEMBL4253131 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 57 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160185743-A1 | 15-Oxospiramilactone Derivatives, Preparation Method and Uses Thereof | CENTER FOR EXCELLENCE IN MOLECULAR CELL SCIENCE, CHINESE ACADEMY OF SCIENCES (CN) | 2016-06-30 | — | — | US | claimed |
| EP-2351753-B1 | PHENANTHROINDOLIZIDINE DERIVATIVE AND NF kB INHIBITOR CONTAINING SAME AS ACTIVE INGREDIENT | YAKULT HONSHA KK (JP) | 2015-02-11 | — | — | EP | claimed |
| US-8569327-B2 | Phenanthroindolizidine derivative and NFκB inhibitor containing same as active ingredient | KABUSHIKI KAISHA YAKULT HONSHA (JP) | 2013-10-29 | — | — | US | claimed |
| US-20110201637-A1 | PHENANTHROINDOLIZIDINE DERIVATIVE AND NFKB INHIBITOR CONTAINING SAME AS ACTIVE INGREDIENT | KABUSHIKI KAISHA YAKULT HONSHA (JP) | 2011-08-18 | — | — | US | claimed |
| EP-2351753-A1 | PHENANTHROINDOLIZIDINE DERIVATIVE AND NF B INHIBITOR CONTAINING SAME AS ACTIVE INGREDIENT | Kabushiki Kaisha Yakult Honsha (JP) | 2011-08-03 | — | — | EP | claimed |
| CN-1294142-C | 17 beta-thiocarboxylate 17 alpha-arylcarbonyloxyandrostane derivatives as anti-inflammatory agents | GLAXO GROUP LTD (GB) | 2007-01-10 | — | — | CN | claimed |
| CN-1468253-A | 17 beta-thiocarboxylate 17 alpha-arylcarbonyloxyandrostane derivatives as anti-inflammatory agents | — | 2004-01-14 | — | — | CN | claimed |
| US-5143936-A | Benzopyran compound and its pharmaceutical use | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1992-09-01 | — | — | US | claimed |
| WO-2023210623-A1 | HALOALKYL SULFONE ANILIDE COMPOUND AND HERBICIDE CONTAINING SAME | 株式会社エス・ディー・エス バイオテック | 2023-11-02 | — | — | WO | disclosed |
| EP-2491915-B1 | EASILY REMOVABLE CURABLE COMPOSITION FOR DENTAL USE | SUN MEDICAL CO LTD (JP) | 2019-07-03 | — | — | EP | disclosed |
| US-10112918-B2 | 15-oxospiramilactone derivatives, preparation method and uses thereof | KUNMING INSTITUTE OF BOTANY, THE CHINESE ACADEMY OF SCIENCES (CN) | 2018-10-30 | — | — | US | disclosed |
| US-20160185743-A1 | 15-Oxospiramilactone Derivatives, Preparation Method and Uses Thereof | CENTER FOR EXCELLENCE IN MOLECULAR CELL SCIENCE, CHINESE ACADEMY OF SCIENCES (CN) | 2016-06-30 | — | — | US | disclosed |
| EP-2351753-B1 | PHENANTHROINDOLIZIDINE DERIVATIVE AND NF kB INHIBITOR CONTAINING SAME AS ACTIVE INGREDIENT | YAKULT HONSHA KK (JP) | 2015-02-11 | — | — | EP | disclosed |
| US-8569324-B2 | Potentiator for radiation therapy comprising pyridine derivative as active ingredient | TAIHO PHARMACEUTICAL CO., LTD. (JP) | 2013-10-29 | — | — | US | disclosed |
| US-4749804-A | Preparation of stereoisomers of ketals | SYNTEX (U.S.A.) INC. (US) | 1988-06-07 | — | — | US | disclosed |
| US-4698339-A | BETA-LACTAMASE INHIBITORS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1987-10-06 | — | — | US | disclosed |
| EP-0226896-A2 | Lankacidin derivatives and production thereof | Takeda Chemical Industries, Ltd. (JP) | 1987-07-01 | — | — | EP | disclosed |
| US-4605758-A | Preparation of α-arylalkanoic acids | SYNTEX PHARMACEUTICALS INTERNATIONAL LTD. (BM) | 1986-08-12 | — | — | US | disclosed |
| EP-0137403-A2 | Carbapenems, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1985-04-17 | — | — | EP | disclosed |
| EP-0081993-A2 | Optically active alpha-substituted aryl ketones, their preparation and their use in preparing alpha-arylalkanoic acids | SYNTEX PHARMACEUTICALS INTERNATIONAL LIMITED (BM) | 1983-06-22 | — | — | EP | disclosed |